Protein Alignment lbl and HOXC4

DIOPT Version :10

• Sequence 1: NP_001262805.1
• Gene: lbl / 42541
• FlyBaseID: FBgn0008651
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_055435.2
• Gene: HOXC4 / 3221
• HGNCID: 5126
• Length: 264
• Species: Homo sapiens
• Alignment Length: 186
• Identity: 56/186 - (30%)
• Similarity: 78/186 - (41%)
• Gaps: 23/186 - (12%)

  Fly   174 GSTECCSPTQA-----EKVEKRSQEDRMEVPKKSPEEQPKGASKSSGDTPLDALFQLSTKNFDEE 233
            |::....|.||     ||.:...:...:.....||...|...|:.:.|.|..|.         .:
Human    76 GNSRGHGPAQAGHHHPEKSQSLCEPAPLSGASASPSPAPPACSQPAPDHPSSAA---------SK 131

  Fly   234 QD---PATLNIFATRSNPK----KKRKSRTAFTNQQIFELEKRFLYQKYLSPADRDEIAGGLGLS 291
            |.   |....|..:..||.    :.::||||:|.||:.||||.|.|.:||:...|.|||..|.||
Human   132 QPIVYPWMKKIHVSTVNPNYNGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLS 196

  Fly   292 NAQVITWFQNRRAKLKRDMEELKKDVQCEKIPDQSADPNRSHHNHPHYHQQHQHYA 347
            ..|:..||||||.|.|:|  ....:.:....|...|.|:......|...:.|...|
Human   197 ERQIKIWFQNRRMKWKKD--HRLPNTKVRSAPPAGAAPSTLSAATPGTSEDHSQSA 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	45/132 (34%)
		Homeodomain	252..308	CDD:459649	30/55 (55%)
HOXC4	NP_055435.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..130		13/62 (21%)
		Antp-type hexapeptide	135..140		1/4 (25%)
		Homeodomain	157..213	CDD:459649	30/55 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..264		7/39 (18%)