Protein Alignment lbl and HOXB9

DIOPT Version :10

• Sequence 1: NP_001262805.1
• Gene: lbl / 42541
• FlyBaseID: FBgn0008651
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_076922.1
• Gene: HOXB9 / 3219
• HGNCID: 5120
• Length: 250
• Species: Homo sapiens
• Alignment Length: 305
• Identity: 76/305 - (24%)
• Similarity: 107/305 - (35%)
• Gaps: 98/305 - (32%)

  Fly    40 LEHDRQKSSPVRVKSFSIADILGRGHEEDRVEKKPERIAIPNA--LPGVP------APLALINER 96
            :.|:.:.:.|.:..|...|.....||        .|.:..|:.  .|..|      |||: .:..
Human    16 ISHESEDAPPAKFPSGQYASSRQPGH--------AEHLEFPSCSFQPKAPVFGASWAPLS-PHAS 71

  Fly    97 LQIPLV------PNCPPPAA---LHTFLSPALLHSYEQRLAWDYQRQLQEHFQAQAQLLRQMTLN 152
            ..:|.|      |...|||.   |.|:|.||             .|......|.||.:..:..|.
Human    72 GSLPSVYHPYIQPQGVPPAESRYLRTWLEPA-------------PRGEAAPGQGQAAVKAEPLLG 123

  Fly   153 PAIIASEDGSSERSQRSSS------SN-----GSTECCSPTQAEKVEKRSQEDRMEVPKKSPEEQ 206
            ......:.|:.|.|..:|:      ||     |..:.|          ...||:         |:
Human   124 APGELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKIC----------EGSEDK---------ER 169

  Fly   207 PKGASKSSGDTPLDALFQLSTKNFDEEQDPATLNIFATRSNPKKKRKSRTAFTNQQIFELEKRFL 271
            |                         :|...:.|....||:    ||.|..:|..|..||||.||
Human   170 P-------------------------DQTNPSANWLHARSS----RKKRCPYTKYQTLELEKEFL 205

  Fly   272 YQKYLSPADRDEIAGGLGLSNAQVITWFQNRRAKLKRDMEELKKD 316
            :..||:...|.|:|..|.||..||..||||||.|:|:..:|..|:
Human   206 FNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNKEQGKE 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	36/111 (32%)
		Homeodomain	252..308	CDD:459649	28/55 (51%)
HOXB9	NP_076922.1	Hox9_act	1..172	CDD:461369	41/221 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	21..47		6/33 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	149..182		10/76 (13%)
		Homeodomain	186..242	CDD:459649	28/55 (51%)