Protein Alignment lbl and HOXB6

DIOPT Version :10

• Sequence 1: NP_001262805.1
• Gene: lbl / 42541
• FlyBaseID: FBgn0008651
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: XP_011523029.1
• Gene: HOXB6 / 3216
• HGNCID: 5117
• Length: 288
• Species: Homo sapiens
• Alignment Length: 255
• Identity: 68/255 - (26%)
• Similarity: 94/255 - (36%)
• Gaps: 53/255 - (20%)

  Fly   103 PNCPPPAALHTFLS---PALLHSYEQRLAWDYQRQLQEHFQAQAQLLRQMTLNPAIIASEDGSSE 164
            |..||......|::   |..|.|.::    .:..||..:....|..||..   ||......|..:
Human    58 PRAPPLPMSSYFVNSTFPVTLASGQE----SFLGQLPLYSSGYADPLRHY---PAPYGPGPGQDK 115

  Fly   165 RSQRSS------SSNGSTECC--SPTQAEKVEKRS---------QEDRMEVPKKSPEEQPKGASK 212
            ....||      ...|....|  .|..|...||.|         |......|:||...|.|..
Human   116 GFATSSYYPPAGGGYGRAAPCDYGPAPAFYREKESACALSGADEQPPFHPEPRKSDCAQDKSV-- 178

  Fly   213 SSGDTPLDALFQLSTKNFDEEQDPAT--------LNIFATRSNPKKKRKSRTAFTNQQIFELEKR 269
             .|:|              |||..:|        :|...:.|.....|:.|..:|..|..||||.
Human   179 -FGET--------------EEQKCSTPVYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEKE 228

  Fly   270 FLYQKYLSPADRDEIAGGLGLSNAQVITWFQNRRAKLKRDMEELK-KDVQCEKIPDQSAD 328
            |.|.:||:...|.|||..|.|:..|:..||||||.|.|::.:.|. ..:..|:..::.|:
Human   229 FHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEEEEEKQAE 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	40/132 (30%)
		Homeodomain	252..308	CDD:459649	26/55 (47%)
HOXB6	XP_011523029.1	Homeodomain	211..267	CDD:459649	26/55 (47%)