Protein Alignment lbl and HOXA9

DIOPT Version :10

• Sequence 1: NP_001262805.1
• Gene: lbl / 42541
• FlyBaseID: FBgn0008651
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_689952.1
• Gene: HOXA9 / 3205
• HGNCID: 5109
• Length: 272
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 84/325 - (25%)
• Similarity: 119/325 - (36%)
• Gaps: 91/325 - (28%)

  Fly     9 ANSDVSVGSPSP-----PPLRSLNMKRLRLLRSPISLEHDRQKSSPVRVKSF-SIADILGRGHEE 67
            |..::|||..:|     ||.::..:           .||  ...||.   || |.|.:.|
Human    21 AADELSVGRYAPGTLGQPPRQAATL-----------AEH--PDFSPC---SFQSKATVFG----- 64

  Fly    68 DRVEKKPERIAIPNALPGVPAPLALINERLQIPLV-PNCPPPAA------LHTFLSP---ALLHS 122
              ....|...|..||:|.     |:.:.....|.| |..|..||      :.::|.|   ||  |
Human    65 --ASWNPVHAAGANAVPA-----AVYHHHHHHPYVHPQAPVAAAAPDGRYMRSWLEPTPGAL--S 120

  Fly   123 YEQRLAWDYQRQLQEHFQAQAQLLRQMTLNPAIIASEDGSSERSQRSSSSNGSTECCSPTQAEKV 187
            :                 |.....|...:.|..:::..|........:.|.....|.||
Human   121 F-----------------AGLPSSRPYGIKPEPLSARRGDCPTLDTHTLSLTDYACGSP------ 162

  Fly   188 EKRSQEDRMEVPKKSPEEQPKGASKSSGD-TPLDALFQLSTKNFDEEQDPATLNIFATRSNPKKK 251
                ..||.:.|.:....:....::|.|| .|:|            ..:||. |....||.
Human   163 ----PVDREKQPSEGAFSENNAENESGGDKPPID------------PNNPAA-NWLHARST---- 206

  Fly   252 RKSRTAFTNQQIFELEKRFLYQKYLSPADRDEIAGGLGLSNAQVITWFQNRRAKLKRDMEELKKD 316
            ||.|..:|..|..||||.||:..||:...|.|:|..|.|:..||..||||||.|:|:..::..||
Human   207 RKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINKDRAKD 271

  Fly   317  316
            Human   272  271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	40/112 (36%)
		Homeodomain	252..308	CDD:459649	27/55 (49%)
HOXA9	NP_689952.1	Hox9_act	1..193	CDD:461369	49/240 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	155..198		12/64 (19%)
		Homeodomain	207..263	CDD:459649	27/55 (49%)