Protein Alignment lbl and nkx2.2a

DIOPT Version :10

• Sequence 1: NP_001262805.1
• Gene: lbl / 42541
• FlyBaseID: FBgn0008651
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_571497.2
• Gene: nkx2.2a / 30697
• ZFINID: ZDB-GENE-980526-403
• Length: 273
• Species: Danio rerio
• Alignment Length: 215
• Identity: 60/215 - (27%)
• Similarity: 91/215 - (42%)
• Gaps: 42/215 - (19%)

  Fly   149 MTLNPAIIASEDGSS--------ERSQRSSSSNGSTECCSPTQAEK----VEKRSQEDRMEVPKK 201
            |..|.::..::.|.|        :.:....|..|:.|....::|.|    :.:...|:...:|.|
Zfish     1 MLQNMSLTNTKTGFSVKDILDLPDTNDEEGSITGTEEDTEGSEATKTPGVLVQSPLENVQNLPLK 65

  Fly   202 SP----EEQP---------------KGASKSSGDTPLDALFQLSTKNFDEEQDPATLNIFATRSN 247
            :|    .:.|               .|.|.:|.||        |.|:.:...|.:..|...|.||
Zfish    66 NPFYDNSDNPYTRWLATTDSIQYSLHGLSANSQDT--------SAKSPEPSADESPDNDKETSSN 122

  Fly   248 PK---KKRKSRTAFTNQQIFELEKRFLYQKYLSPADRDEIAGGLGLSNAQVITWFQNRRAKLKRD 309
            ..   ||||.|..|:..|.:|||:||..|:|||..:|:.:|..:.|:..||..||||.|.|:||.
Zfish   123 GSDSGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKRA 187

  Fly   310 MEELKKDVQCEKIPDQSADP 329
            ..|...:|.....|.:.|.|
Zfish   188 RAEKGMEVTHLPSPRRVAVP 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	47/142 (33%)
		Homeodomain	252..308	CDD:459649	25/55 (45%)
nkx2.2a	NP_571497.2	COG5576	93..218	CDD:227863	45/123 (37%)
		Homeodomain	130..186	CDD:459649	25/55 (45%)