Protein Alignment lbl and nkx2.5

DIOPT Version :10

• Sequence 1: NP_001262805.1
• Gene: lbl / 42541
• FlyBaseID: FBgn0008651
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_571496.2
• Gene: nkx2.5 / 30696
• ZFINID: ZDB-GENE-980526-321
• Length: 314
• Species: Danio rerio
• Alignment Length: 215
• Identity: 64/215 - (29%)
• Similarity: 89/215 - (41%)
• Gaps: 59/215 - (27%)

  Fly   143 AQLLRQMTLNPAIIA--------SED-GSSERSQRSSSSNGSTECCSPTQAEKVEKRSQEDRMEV 198
            |....|||..|..:.        .|| .|.:.|||..|:      ..||.:..:....||..||:
Zfish     2 AMFSSQMTSTPFSVRDILNLEQNQEDMVSLDMSQRLDSA------LIPTSSCMLSTFKQEQFMEM 60

  Fly   199 PKKSPEEQPKGASKSSGDTPLDALFQLSTKNF-------------DEEQDPATLNIF-------- 242
                    |.|:|..|.|...|...::::.||             |..:|..|.:.|
Zfish    61 --------PSGSSLFSEDLQEDKGNKINSINFSASGFYAKNFLEMDYVKDAKTDDTFEDKEKKDI 117

  Fly   243 ---------------ATRSNPKKKRKSRTAFTNQQIFELEKRFLYQKYLSPADRDEIAGGLGLSN 292
                           |.|...:|:||.|..|:..|::|||:||..|||||..:||.:|..|.|::
Zfish   118 GCCQEDPGEDLKLDDAERPKQRKRRKPRVLFSQAQVYELERRFKQQKYLSAPERDHLANVLKLTS 182

  Fly   293 AQVITWFQNRRAKLKRDMEE 312
            .||..||||||.|.||..::
Zfish   183 TQVKIWFQNRRYKCKRQRQD 202

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	46/143 (32%)
		Homeodomain	252..308	CDD:459649	29/55 (53%)
nkx2.5	NP_571496.2	Homeodomain	142..198	CDD:459649	29/55 (53%)