Protein Alignment lbl and Nkx1-2

DIOPT Version :9

• Sequence 1: NP_001262805.1
• Gene: lbl / 42541
• FlyBaseID: FBgn0008651
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_001163947.1
• Gene: Nkx1-2 / 293568
• RGDID: 1306744
• Length: 305
• Species: Rattus norvegicus
• Alignment Length: 302
• Identity: 73/302 - (24%)
• Similarity: 114/302 - (37%)
• Gaps: 93/302 - (30%)

  Fly    46 KSSPVRVK-SFSIADILGRGHEEDRVEKKPERIAIPNALPGVPAPLALINERLQIPLVPNCPPPA 109
            |::|...| |||:.|||.        .:|..|.|:|      |..||.:
  Rat    10 KAAPSHHKISFSVLDILD--------PQKFTRAALP------PVRLAAL---------------- 44

  Fly   110 ALHTFLSPALLHSYEQRLAWDYQRQLQEHFQAQAQLLRQMTLNPAIIASED---GSSERSQRSSS 171
                                          :|:..|:.       :.|.||   |:...||.:..
  Rat    45 ------------------------------EAKKSLVE-------VEAGEDACSGNPIGSQETPD 72

  Fly   172 S-NGSTECCSPTQAEKVEKRSQEDRMEVPKKSPEEQPKGASKSSGDTPLDA-LFQLSTKNFDEEQ 234
            : .|.|:..||.:..:.|:  :|:..:..:....|:.:||...|    |:| ...:.|:....:.
  Rat    73 AVGGGTDPASPVEGSEAEE--EEEAEDAGRAQRPERWQGAHAGS----LEAGAVAVGTEESGADG 131

  Fly   235 DPATLNIFATRSNPK-----------KKRKSRTAFTNQQIFELEKRFLYQKYLSPADRDEIAGGL 288
            .||:.   .:..:|:           |.|::|||||.:|:..||.:|...:|||..:|..:|..|
  Rat   132 LPASP---GSPGSPRPRRRRAESSCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSL 193

  Fly   289 GLSNAQVITWFQNRRAKLKRDMEELKKDVQCEKIPDQSADPN 330
            .|:..||..||||||.|.|:........||......|...||
  Rat   194 SLTETQVKIWFQNRRTKWKKQNPGADGAVQAGGSAPQPGTPN 235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	42/137 (31%)
		Homeobox	254..307	CDD:278475	25/52 (48%)
Nkx1-2	NP_001163947.1	Homeobox	160..213	CDD:395001	25/52 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900