Protein Alignment lbl and Tlx3

DIOPT Version :10

• Sequence 1: NP_001262805.1
• Gene: lbl / 42541
• FlyBaseID: FBgn0008651
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: XP_036012630.1
• Gene: Tlx3 / 27140
• MGIID: 1351209
• Length: 338
• Species: Mus musculus
• Alignment Length: 357
• Identity: 81/357 - (22%)
• Similarity: 118/357 - (33%)
• Gaps: 154/357 - (43%)

  Fly     2 PQRTPSPANSDVSVGSPSPPPLRSLNMKRLRLLRSPISLEHDRQKSSPVRVKSFSIADILGRGHE 66
            |:|...||.|..|...|..||          .:.:|.|    .|...|....||.|
Mouse    26 PRRNGDPAASPPSPAQPFRPP----------RMEAPAS----AQTPHPHEPISFGI--------- 67

  Fly    67 EDRVEKKPERIAIP--------------------NALPGVP----------------------AP 89
             |::...|::.:.|                    .|.|.:|                      ||
Mouse    68 -DQILNSPDQDSAPAPRGPDGASYLGGPPGGRPGAAYPSLPASFAGLGAPFEDAGSYSVNLSLAP 131

  Fly    90 LALINERLQIPLVPNCPP--PAALHTFLSPALLHSYEQRLAWDYQRQLQEHFQAQAQLLRQMTLN 152
            ..:|......||....||  |:||     ||:
Mouse   132 AGVIRVPAHRPLPGAVPPPLPSAL-----PAM--------------------------------- 158

  Fly   153 PAI--IASEDGSSERSQRSSSSNGSTECCSPTQAEKVEKRSQEDRMEVPKKSPEEQPKGASKSSG 215
            |::  ::|..|.:.....||                  :|..:||.              :.::.
Mouse   159 PSVPTVSSLGGLNFPWMESS------------------RRFVKDRF--------------TAAAA 191

  Fly   216 DTPLDALFQLSTKNFDEEQDPATLNIFATRSNPKKKRKSRTAFTNQQIFELEKRFLYQKYLSPAD 280
            .||.....::.             :.:..|:.||:| |.||:|:..||.||||||..||||:.|:
Mouse   192 LTPFTVTRRIG-------------HPYQNRTPPKRK-KPRTSFSRVQICELEKRFHRQKYLASAE 242

  Fly   281 RDEIAGGLGLSNAQVITWFQNRRAKLKRDMEE 312
            |..:|..|.:::|||.|||||||.|.:|...|
Mouse   243 RAALAKSLKMTDAQVKTWFQNRRTKWRRQTAE 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	39/107 (36%)
		Homeodomain	252..308	CDD:459649	31/55 (56%)
Tlx3	XP_036012630.1	PRK07764	<20..>109	CDD:236090	22/106 (21%)
		Homeodomain	214..270	CDD:459649	32/56 (57%)