Protein Alignment lbl and Nkx1-2

DIOPT Version :9

• Sequence 1: NP_001262805.1
• Gene: lbl / 42541
• FlyBaseID: FBgn0008651
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_033149.1
• Gene: Nkx1-2 / 20231
• MGIID: 104806
• Length: 305
• Species: Mus musculus
• Alignment Length: 279
• Identity: 66/279 - (23%)
• Similarity: 107/279 - (38%)
• Gaps: 91/279 - (32%)

  Fly    46 KSSPVRVK-SFSIADILGRGHEEDRVEKKPERIAIPNALPGVPAPLALINERLQIPLVPNCPPPA 109
            |::|...| |||:.|||.        .:|..|.|:|      |..||
Mouse    10 KAAPSHHKISFSVLDILD--------PQKFTRAALP------PVRLA------------------ 42

  Fly   110 ALHTFLSPALLHSYEQRLAWDYQRQLQEHFQAQAQLLRQMTLNPAIIASED---GSSERSQRSSS 171
                              |.:.::.|:|                 :.|.:|   |:...||.:..
Mouse    43 ------------------ALEAKKSLEE-----------------VEAGQDACSGNPIGSQETPD 72

  Fly   172 SNG-STECCSPTQAEKVEKRSQEDRMEVPKKSPEEQPKGASKSSGDTPLDALFQLSTKNFDEEQD 235
            :.| ..:..||.:..:.|:  :|:..:..:....|:.:|..:.|   |......:.|:....|..
Mouse    73 AVGRGIDPGSPVEGSEAEE--EEEAEDAGRAHQPERWQGVHEGS---PEARAVAVGTEESGAEGL 132

  Fly   236 PATLNIFATRSNPK-----------KKRKSRTAFTNQQIFELEKRFLYQKYLSPADRDEIAGGLG 289
            ||:.   .:..:|:           |.|::|||||.:|:..||.:|...:|||..:|..:|..|.
Mouse   133 PASP---GSPGSPRPRRRRAESSCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLS 194

  Fly   290 LSNAQVITWFQNRRAKLKR 308
            |:..||..||||||.|.|:
Mouse   195 LTETQVKIWFQNRRTKWKK 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	36/114 (32%)
		Homeobox	254..307	CDD:278475	25/52 (48%)
Nkx1-2	NP_033149.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	51..158		21/131 (16%)
		Homeobox	160..212	CDD:278475	25/51 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	210..257		2/4 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900