DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment lbl and tlx2

DIOPT Version :9

Sequence 1:NP_001262805.1 Gene:lbl / 42541 FlyBaseID:FBgn0008651 Length:410 Species:Drosophila melanogaster
Sequence 2:XP_005173139.1 Gene:tlx2 / 170781 ZFINID:ZDB-GENE-020208-1 Length:309 Species:Danio rerio


Alignment Length:154 Identity:53/154 - (34%)
Similarity:77/154 - (50%) Gaps:25/154 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   226 STKNFDEEQDPATLNIFA-TR--------SNPKKKRKSRTAFTNQQIFELEKRFLYQKYLSPADR 281
            |::.|.:::..|.|:.|: ||        ..|.|::|.||:|:..||.||||||..||||:.|:|
Zfish   148 SSRRFAKDRLTAALSPFSVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAER 212

  Fly   282 DEIAGGLGLSNAQVITWFQNRRAKLKRDMEE-----------LKKDVQCEKIPDQSADPNRSH-- 333
            ..:|..|.:::|||.|||||||.|.:|...|           |...:|.|......:.|.:..  
Zfish   213 ATLAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRLMLQLQQEAFQKTLSQPLQQDPL 277

  Fly   334 --HNHPHYHQQH-QHYAHMQSIGS 354
              ||...|..|: |.:|....:.|
Zfish   278 CLHNSSLYALQNLQPWAEDNKVTS 301

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
lblNP_001262805.1 COG5576 206..332 CDD:227863 46/125 (37%)
Homeobox 254..307 CDD:278475 30/52 (58%)
tlx2XP_005173139.1 Homeobox 185..238 CDD:278475 30/52 (58%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0488
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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