Protein Alignment lbl and Hoxd11

DIOPT Version :10

• Sequence 1: NP_001262805.1
• Gene: lbl / 42541
• FlyBaseID: FBgn0008651
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_032299.1
• Gene: Hoxd11 / 15431
• MGIID: 96203
• Length: 336
• Species: Mus musculus
• Alignment Length: 262
• Identity: 62/262 - (23%)
• Similarity: 93/262 - (35%)
• Gaps: 77/262 - (29%)

  Fly    64 GHEEDRVEKKPERIAIPNALPGVPAPLALINERLQIPLVPNCPPPAALHTFLSPA-----LLHSY 123
            |...|.:.|.||.:.      |.|.|             |: .|.||...|.|..     |...:
Mouse   132 GRRPDVLFKAPEPVC------GAPGP-------------PH-GPAAAASNFYSAVGRNGILPQGF 176

  Fly   124 EQRLAWDYQRQLQEHFQAQAQLLRQMTLNPAIIASEDGSSERSQRSSSSNGSTECCSPTQAEKVE 188
            :|    .|:......|...     |....||....|..:.:...:..:..|....|:
Mouse   177 DQ----FYEAAPGPPFAGP-----QPQPAPAPPQPEGAADKGDPKPGAGGGGGSPCA-------- 224

  Fly   189 KRSQEDRMEVPKKSPEEQPKGASKSSGDTPLDALFQLSTKNFDEEQDPATLNIFATRSN----PK 249
                       |.:|..:||||::..|.              :.|..|....  |.:|.    |:
Mouse   225 -----------KATPGPEPKGAAEGGGG--------------EGEGPPGEAG--AEKSGGTVAPQ 262

  Fly   250 KKRKSRTAFTNQQIFELEKRFLYQKYLSPADRDEIAGGLGLSNAQVITWFQNRRAKLKRDMEELK 314
            :.||.|..:|..||.|||:.|.:..|::...|.:::..|.|::.||..||||||.|.|:    |.
Mouse   263 RSRKKRCPYTKYQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKK----LN 323

  Fly   315 KD 316
            :|
Mouse   324 RD 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	36/115 (31%)
		Homeodomain	252..308	CDD:459649	23/55 (42%)
Hoxd11	NP_032299.1	DUF3528	26..187	CDD:432284	17/78 (22%)
		Homeodomain	265..321	CDD:459649	23/55 (42%)