Protein Alignment lbl and Hoxb4

DIOPT Version :10

• Sequence 1: NP_001262805.1
• Gene: lbl / 42541
• FlyBaseID: FBgn0008651
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_034589.3
• Gene: Hoxb4 / 15412
• MGIID: 96185
• Length: 250
• Species: Mus musculus
• Alignment Length: 245
• Identity: 61/245 - (24%)
• Similarity: 83/245 - (33%)
• Gaps: 95/245 - (38%)

  Fly    84 PGVPAPLALINERLQIPLVPNCPPPAALHTFLSPALLHSYEQRLAWDYQRQLQEHFQAQAQLLRQ 148
            ||.|.|          |..|..|||..    |||                              :
Mouse    71 PGPPPP----------PPPPPPPPPPG----LSP------------------------------R 91

  Fly   149 MTLNPAIIASEDGSSERSQRSSSSNGSTECCSPTQAEKVEKRSQEDRMEVPKKSPEEQPKGASKS 213
            ..:.|...|......:||:..|||.....|            :|......|..|..::|
Mouse    92 APVQPTAGALLPEPGQRSEAVSSSPPPPPC------------AQNPLHPSPSHSACKEP------ 138

  Fly   214 SGDTPLDALFQLSTKNFDEEQDPATLNIFATRSNPK----KKRKSRTAFTNQQIFELEKRFLYQK 274
                   .::            |....:..:..||.    :.::||||:|.||:.||||.|.|.:
Mouse   139 -------VVY------------PWMRKVHVSTVNPNYAGGEPKRSRTAYTRQQVLELEKEFHYNR 184

  Fly   275 YLSPADRDEIAGGLGLSNAQVITWFQNRRAKLKRDMEELKKDVQCEKIPD 324
            ||:...|.|||..|.||..|:..||||||.|.|:|          .|:|:
Mouse   185 YLTRRRRVEIAHALCLSERQIKIWFQNRRMKWKKD----------HKLPN 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	38/123 (31%)
		Homeodomain	252..308	CDD:459649	30/55 (55%)
Hoxb4	NP_034589.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..133		22/117 (19%)
		Antp-type hexapeptide	140..145		1/16 (6%)
		Homeodomain	162..218	CDD:459649	30/55 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	219..250		3/16 (19%)