Protein Alignment lbl and Dlx3

DIOPT Version :10

• Sequence 1: NP_001262805.1
• Gene: lbl / 42541
• FlyBaseID: FBgn0008651
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_034185.1
• Gene: Dlx3 / 13393
• MGIID: 94903
• Length: 287
• Species: Mus musculus
• Alignment Length: 174
• Identity: 50/174 - (28%)
• Similarity: 74/174 - (42%)
• Gaps: 49/174 - (28%)

  Fly   216 DTPLDALFQLSTKNFDEEQDPATLNIFATRSNPKKKRKSRTAFTNQQIFELEKRFLYQKYLSPAD 280
            :.||.|...:|.|...|.:      :......|||.||.||.:::.|:..|::||...:||:..:
Mouse   100 EQPLPAQDPVSVKEEPEAE------VRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPE 158

  Fly   281 RDEIAGGLGLSNAQVITWFQNRRAKLKRDMEELKK--DVQCEKIPDQS------ADP-----NRS 332
            |.|:|..|||:..||..||||||:|.|:    |.|  :|..|..|:.|      :.|     :.|
Mouse   159 RAELAAQLGLTQTQVKIWFQNRRSKFKK----LYKNGEVPLEHSPNNSDSMACNSPPSPALWDTS 219

  Fly   333 HHNHP--------------------------HYHQQHQHYAHMQ 350
            .|:.|                          .||.|:....|:|
Mouse   220 SHSTPAPARNPLPPPLPYSASPNYLDDPTNSWYHTQNLSGPHLQ 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	42/128 (33%)
		Homeodomain	252..308	CDD:459649	25/55 (45%)
Dlx3	NP_034185.1	DLL_N	27..107	CDD:463567	3/6 (50%)
		COG5576	<109..224	CDD:227863	41/124 (33%)
		Homeodomain	130..186	CDD:459649	25/55 (45%)
		Interaction with DNA. /evidence=ECO:0000250|UniProtKB:O60479	131..181		21/49 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..287		12/69 (17%)