Protein Alignment lbl and Dlx2

DIOPT Version :10

• Sequence 1: NP_001262805.1
• Gene: lbl / 42541
• FlyBaseID: FBgn0008651
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_034184.1
• Gene: Dlx2 / 13392
• MGIID: 94902
• Length: 332
• Species: Mus musculus
• Alignment Length: 289
• Identity: 65/289 - (22%)
• Similarity: 98/289 - (33%)
• Gaps: 120/289 - (41%)

  Fly   157 ASEDGSSERSQRSSSSNGSTECCSPTQAEKVEKRSQEDRMEVPKKSP---------------EEQ 206
            |...|:|    .|||||.|                    :..|::||               ::.
Mouse    35 AGPGGNS----NSSSSNSS--------------------LHKPQESPTLPVSTATDSSYYTNQQH 75

  Fly   207 PKG---------------------------ASKSSGDTPLDALFQ------LSTKNFDEEQDPAT 238
            |.|                           ::|||.|....|.:.      .|:...:.|.|...
Mouse    76 PAGGGGGGASPYAHMGSYQYHASGLNNVSYSAKSSYDLGYTAAYTSYAPYGTSSSPVNNEPDKED 140

  Fly   239 L--NIFATRSNPKKKRKSRTAFTNQQIFELEKRFLYQKYLSPADRDEIAGGLGLSNAQVITWFQN 301
            |  .|......|||.||.||.:::.|:..|::||...:||:..:|.|:|..|||:..||..||||
Mouse   141 LEPEIRIVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQN 205

  Fly   302 RRAKLKRDMEELKKDVQCEKIPDQSADP------------------------------------- 329
            ||:|.|:..:  ..::..|:.|..||.|
Mouse   206 RRSKFKKMWK--SGEIPTEQHPGASASPPCASPPVSAPASWDFGAPQRMAGGGPGSGGGGAGSSG 268

  Fly   330 -------NRSHHNHPHYHQQHQHYAHMQS 351
                   :....|:|.|||.....:|:|:
Mouse   269 SSPSSAASAFLGNYPWYHQASGSASHLQA 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	46/204 (23%)
		Homeodomain	252..308	CDD:459649	25/55 (45%)
Dlx2	NP_034184.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..83		14/71 (20%)
		DLL_N	54..135	CDD:463567	10/80 (13%)
		Homeodomain	156..212	CDD:459649	25/55 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	219..272		5/52 (10%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	304..332