DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lbl and Barhl1

DIOPT Version :9

Sequence 1:	NP_001262805.1	Gene:	lbl / 42541	FlyBaseID:	FBgn0008651	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	NP_476450.1	Gene:	Barhl1 / 117232	RGDID:	620648	Length:	327	Species:	Rattus norvegicus

Alignment Length:	202	Identity:	60/202 - (29%)
Similarity:	88/202 - (43%)	Gaps:	44/202 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 MTLNPAIIASEDGSSERSQRSSSSNGSTECCSPTQAEKVEKRSQEDRMEVPKKS----------- 202
            :.|:|...:|.|.||..|........||..........::...|..::..|.:|
  Rat    36 LELSPRSESSSDCSSPASPGRDCLETSTSRPGAASGPGLDSHLQPGQLSAPAQSRTVTSSFLIRD 100

  Fly   203 ----------------------PEEQPKGASKSSGD--TPLDALFQLSTKNFDEE---QDPATLN 240
                                  ||...:.|:|:..|  ..||.  .:|:.:.|.|   ::.....
  Rat   101 ILADCKPLAACAPYSSSGQPAAPEPGGRLAAKAGEDFRDKLDK--SVSSASSDSEYKVKEEGDRE 163

  Fly   241 IFATRSNP----KKKRKSRTAFTNQQIFELEKRFLYQKYLSPADRDEIAGGLGLSNAQVITWFQN 301
            |.::|.:|    ||.||:|||||:.|:.:||:.|..|||||..||.|:|..|.|::.||.||:||
  Rat   164 ISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQN 228

  Fly   302 RRAKLKR 308
            ||.|.||
  Rat   229 RRTKWKR 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	46/112 (41%)
lbl	NP_001262805.1	Homeobox	254..307	CDD:278475	29/52 (56%)
Barhl1	NP_476450.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..90		11/53 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	113..181		16/69 (23%)
		Homeobox	182..235	CDD:395001	29/52 (56%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	303..327
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810