Protein Alignment lbl and Gbx2

DIOPT Version :10

• Sequence 1: NP_001262805.1
• Gene: lbl / 42541
• FlyBaseID: FBgn0008651
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_446160.1
• Gene: Gbx2 / 114500
• RGDID: 621866
• Length: 348
• Species: Rattus norvegicus
• Alignment Length: 354
• Identity: 92/354 - (25%)
• Similarity: 130/354 - (36%)
• Gaps: 96/354 - (27%)

  Fly    54 SFSIADILGRGHEEDRVEKKPERIAIPNALPG----VPAPLALINERLQIPLVPNCPPPAALHTF 114
            :|||..::|               :.|...||    ...|:.:....:.:| .|..||||.....
  Rat    21 AFSIDSLIG---------------SPPQPSPGHFVYTGYPMFMPYRPVVLP-PPPPPPPALPQAA 69

  Fly   115 LSPAL--LHSYEQ----------------RLAWDYQRQLQEHFQA-----QAQLLRQMTLNPAII 156
            |.|||  .|.:.|                .|.......|...|.|     :|...|:....|...
  Rat    70 LQPALPPAHPHHQIPSLPTGFCSSLAQGMALTSTLMATLPGGFSASPQHQEAAAARKFAPQPLPG 134

  Fly   157 ASEDGSSERSQRSS-------SSNGSTECCSPTQAEKVE----KRSQ-EDRMEVPKKSPEEQPKG 209
            ......||..|..:       :..||....|..:|.:..    .|.| :|..:|     |:.|||
  Rat   135 GGNFDKSEALQADTEDGKAFLAKEGSLLAFSAAEAVQASLVGAVRGQGKDESKV-----EDDPKG 194

  Fly   210 ASKS---SGDTPLDALFQLSTKNFDEEQDPATLNIFATRSNPK------------KKRKSRTAFT 259
            ..:|   ..|....:...|..:...:|:||.    .|....|:            |.|:.|||||
  Rat   195 KEESFSLESDVDYSSDDNLPGQTAHKEEDPG----HALEETPQSGGAAGSTTSTGKNRRRRTAFT 255

  Fly   260 NQQIFELEKRFLYQKYLSPADRDEIAGGLGLSNAQVITWFQNRRAKLKRDMEELKKDVQCEKIPD 324
            ::|:.||||.|..:||||..:|.:||..|.||..||..||||||||.||        |:......
  Rat   256 SEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKR--------VKAGNANS 312

  Fly   325 QSADPNRS---------HHNHPHYHQQHQ 344
            ::.:|:|:         |.:......|||
  Rat   313 KTGEPSRNPKIVVPIPVHVSRFAIRSQHQ 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	48/140 (34%)
		Homeodomain	252..308	CDD:459649	32/55 (58%)
Gbx2	NP_446160.1	Homeodomain	248..304	CDD:459649	32/55 (58%)