Protein Alignment lbl and nkx1-2

DIOPT Version :10

• Sequence 1: NP_001262805.1
• Gene: lbl / 42541
• FlyBaseID: FBgn0008651
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: XP_002937845.1
• Gene: nkx1-2 / 100486193
• XenbaseID: XB-GENE-854960
• Length: 246
• Species: Xenopus tropicalis
• Alignment Length: 226
• Identity: 61/226 - (26%)
• Similarity: 89/226 - (39%)
• Gaps: 60/226 - (26%)

  Fly   176 TECCSPTQAEKVEKRSQEDRMEVPKKSPEEQPKGASKSSGDT----PLDAL-----FQLSTKNFD 231
            |:..:..:.::|::.:||..|               |..|||    |.|::     .:..|...:
 Frog    27 TDILNHAKVQQVKEGTQEPGM---------------KEKGDTGLTLPSDSMVSGPEIKAETSPGE 76

  Fly   232 EEQDPATLNIFATRSNPK----KKRKSRTAFTNQQIFELEKRFLYQKYLSPADRDEIAGGLGLSN 292
            .|:.|.......|::.|.    |.|::|||||.:|:..||.||...:|||..:|..:|..|.|:.
 Frog    77 PEELPEKEENQETQNVPSVTNCKPRRARTAFTYEQLVALESRFRSSRYLSVCERLSLALTLHLTE 141

  Fly   293 AQVITWFQNRRAKLKR-----DMEELKKDVQ-CEKIPDQSAD---PNRSHHNH-PHYHQQHQHYA 347
            .||..||||||.|.|:     .:|.....:| |..||.....   ||.....| ||......|.:
 Frog   142 TQVKIWFQNRRTKWKKQQPIGSLEGRGCSIQNCPTIPGPRFTPPLPNYPCATHIPHIGAGANHLS 206

  Fly   348 ----------------------HMQSIGSDR 356
                                  :.|.|||.|
 Frog   207 PFPGIFFSPPSTSFGLSPTGATYPQFIGSSR 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	47/147 (32%)
		Homeodomain	252..308	CDD:459649	27/55 (49%)
nkx1-2	XP_002937845.1	Homeodomain	101..157	CDD:459649	27/55 (49%)