Protein Alignment lbl and hoxd12a

DIOPT Version :10

• Sequence 1: NP_001262805.1
• Gene: lbl / 42541
• FlyBaseID: FBgn0008651
• Length: 410
• Species: Drosophila melanogaster
• Sequence 2: NP_001119958.1
• Gene: hoxd12a / 100006598
• ZFINID: ZDB-GENE-990415-118
• Length: 277
• Species: Danio rerio
• Alignment Length: 258
• Identity: 71/258 - (27%)
• Similarity: 100/258 - (38%)
• Gaps: 58/258 - (22%)

  Fly   109 AALHTFLSPALLH-----------------SYEQR----LAWDYQRQLQEHFQAQAQ-------L 145
            |.|..|.||..|:                 ||.:|    |.|..........|::|.       .
Zfish    13 APLLNFHSPDSLYLQNLRGNGVHLSGLPQMSYSRREVCSLPWSSSNSCTAPAQSRAYSGYSQPFF 77

  Fly   146 LRQMTLNPAIIASEDGSSERSQR---SSSSNGSTECCSPTQAEKVEKRSQE------DRMEVPKK 201
            .....::.::...:.||.|.|.|   ...|:.|.|...|..|...|:.|..      :|.::...
Zfish    78 SNSAAVSASLNTHKKGSLEESGRYYFQDVSHKSEEPGRPNAAYASEQSSASNGLSNLERRQLNAV 142

  Fly   202 SPE-----EQPKG-ASKSSGDTPLDALFQ--LSTKNFDEEQDPATLNI------FATRSNP---- 248
            :|.     |||:. |||.|..:  .|.||  ||.:|........|||.      ..|...|
Zfish   143 APNELSCIEQPESDASKQSVSS--IAPFQPSLSAQNIRPAFTDGTLNFSNDPSAIDTNGLPWCPS 205

  Fly   249 -KKKRKSRTAFTNQQIFELEKRFLYQKYLSPADRDEIAGGLGLSNAQVITWFQNRRAKLKRDM 310
             .:.||.|..:|..|:.|||..|:..::::...|.|::..|.||:.||..||||||.|.||.|
Zfish   206 QVRSRKKRKPYTKPQLTELENEFMMNEFINRQKRKELSDRLELSDQQVKIWFQNRRMKKKRLM 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbl	NP_001262805.1	COG5576	206..332	CDD:227863	43/119 (36%)
		Homeodomain	252..308	CDD:459649	23/55 (42%)
hoxd12a	NP_001119958.1	Homeodomain	210..266	CDD:459649	23/55 (42%)