Protein Alignment Ugt49B2 and Ugt2a1

DIOPT Version :10

• Sequence 1: NP_001097859.4
• Gene: Ugt49B2 / 42538
• FlyBaseID: FBgn0038886
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_444414.2
• Gene: Ugt2a1 / 94215
• MGIID: 2149905
• Length: 528
• Species: Mus musculus
• Alignment Length: 534
• Identity: 163/534 - (30%)
• Similarity: 267/534 - (50%)
• Gaps: 67/534 - (12%)

  Fly     5 MKLLFVC-----LLGTGDGARILAPFFLPVK-SHFMMTDAIIRELVKRGHEVT--------FITP 55
            :|.:.:|     |||...|..:|   ..|:: ||::....||.||:::.|.||        ||||
Mouse     2 LKNILLCSLQISLLGMSLGGNVL---IWPMEGSHWLNVKIIIDELLRKEHNVTVLVASGALFITP 63

  Fly    56 LSLA-------------KENLGPNYREILLPKYDTWADISAMMKT-----KSALDMIDMSKLTHM 102
            .|::             ||.:....::.:|    ||.:......|     |....:|:...|...
Mouse    64 SSISPSLTFEIYPVPFGKEKIESVIKDFVL----TWLENRPSPSTIWTFYKEMAKVIEEFHLVSR 124

  Fly   103 RLAQHIGIKSTDFALAHPEVQELIYAKDKKGKFDLLLVEQFHNEG---ALMLGYIYEIPAITIAT 164
            .:...: :|:           |.:.:|.:|.||::||.:.....|   ||.||    ||.|....
Mouse   125 GICDGV-LKN-----------EKLMSKLQKEKFEVLLSDPVFPCGDIVALKLG----IPFIYSLR 173

  Fly   165 FAYANYFSQVFGFVN-PLSYVPNVFLSCTDRMSLWERLENVVISTAEDVVREVSYYPQQDAVIRK 228
            |:.|:...:..|.|. |.||||.:....||:||..:|:.|.:....:|.:.| :.:.|.|:
Mouse   174 FSPASTVEKHCGKVPFPPSYVPAILSELTDQMSFTDRVRNFISYRMQDYMFE-TLWKQWDS---- 233

  Fly   229 HFSSLLPRVPTVKQLEQNISVILLNSYMPLTSPRPMSQNMISVGGLHILPPKPLPEHIKNYLD-N 292
            :::..|.|..|:.:......:.|:.:|.....|||...|...|||||..|.||||:.::.::. :
Mouse   234 YYTKALGRPTTLCETMGKAEIWLMRTYWDFEFPRPYLPNFEFVGGLHCKPAKPLPKEMEEFVQTS 298

  Fly   293 AEHGAIYFSLGSQVRSADMPAEKLQIFLDVFASLKQRVLWKFEDDQLPNLPDNVKVEKWLPQADI 357
            .|||.:.|||||.|:  ::..||..:.....|.:.|:|||:::......|..|.::..|:||.|:
Mouse   299 GEHGIVVFSLGSMVK--NLTDEKANLIASALAQIPQKVLWRYKGKIPDTLGSNTRLFDWIPQNDL 361

  Fly   358 LAHPNVKVFIAHGGLFGMQEAVYHAVPVLGMPFYFDQDINIKAGQAAGYAIGLDYRTISKDQLKS 422
            |.||..:.||.|||..|:.||:||.:|::|:|.:.||..||...:|.|.|:.::..|::...|.:
Mouse   362 LGHPKTRAFITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSSDLLN 426

  Fly   423 ALHALLKDPKYQANMMKASRIFRDRPLGAMDTAMYWINYVVEHRGAPHLVAAGVHLPWYQFYLLD 487
            ||..::.:|.|:.|.|:.|||..|:|:..:|.|::||.:|:.|:||.||..|...|.|:|::.||
Mouse   427 ALRTVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLD 491

  Fly   488 VSAIILAITLLPLL 501
            |...:||.....:|
Mouse   492 VIGFLLACVASAIL 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B2	NP_001097859.4	Glycosyltransferase_GTB-type	31..497	CDD:471961	154/496 (31%)
Ugt2a1	NP_444414.2	UDPGT	21..516	CDD:278624	157/515 (30%)