Protein Alignment Ugt49B2 and Ugt2b35

DIOPT Version :10

• Sequence 1: NP_001097859.4
• Gene: Ugt49B2 / 42538
• FlyBaseID: FBgn0038886
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001004271.1
• Gene: Ugt2b35 / 83808
• RGDID: 620895
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 567
• Identity: 177/567 - (31%)
• Similarity: 286/567 - (50%)
• Gaps: 89/567 - (15%)

  Fly     2 ILFMKLLFVCLLGTGDGARILAPFFLPVK-SHFMMTDAIIRELVKRGHEVT-------------- 51
            :|.:::.| | ..:|:..::|.   .|:: ||:|....|:.|||::|||||
  Rat     9 LLLLQISF-C-FKSGNCGKVLV---WPMEYSHWMNIKIILEELVQKGHEVTVLRPSASVFLDPKE 68

  Fly    52 -----FIT-PLSLAKENLGPNYREIL------LPKYDTWADISAMMKTKSALDMIDMSKLTHMRL 104
                 |:| |.|.:..:|...:...:      ||: ||.  :|..:..:..:|......||..:.
  Rat    69 TSDLKFVTFPTSFSSHDLENFFTRFVNVWTYELPR-DTC--LSYFLYLQDTIDEYSDYCLTVCKE 130

  Fly   105 AQHIGIKSTDFALAHPEVQELIYAKDKKGKFDLLLVEQFHNEGALMLGYIYEIPAITIATFAYAN 169
            |    :.:..|           ..|.::.|||::..:.....|.| :..:.:||      |.|:.
  Rat   131 A----VSNKQF-----------MTKLQESKFDVVFSDAIGPCGEL-IAELLQIP------FLYSL 173

  Fly   170 YFS-------QVFGFVNPLSYVPNVFLSCTDRMSLWERLENVVISTAED----VVREVSYYPQQD 223
            .||       .:.|.:.|.||||.:|.....:|:..||:.|::.....|    ..||..:.|
  Rat   174 RFSPGYTIEKYIGGVLFPPSYVPMIFSGLAGQMTFIERVHNMICMLYFDFWFQTFREKKWDP--- 235

  Fly   224 AVIRKHFSSLLPRVPTVKQLEQNISVILLNSYMPLTSPRPMSQNMISVGGLHILPPKPLPEHIKN 288
                 .:|..|.|..|:.::.....:.|:.||..|..|.|:|.|:..:||||..|.||||:.|::
  Rat   236 -----FYSKTLGRPTTLAEIMGKAEMWLIRSYWDLEFPHPISPNVDYIGGLHCKPAKPLPKDIED 295

  Fly   289 YLDNA-EHGAIYFSLGSQVRSADMPAEKLQIFLDVFASLKQRVLWKFEDDQLPNLPDNVKVEKWL 352
            ::.:: |||.:.|||||.||  :|..||..|.....|.:.|:|||:|:..:.|.|..|.::.|||
  Rat   296 FVQSSGEHGVVVFSLGSMVR--NMTEEKANIIAWALAQIPQKVLWRFDGKKPPTLGPNTRLYKWL 358

  Fly   353 PQADILAHPNVKVFIAHGGLFGMQEAVYHAVPVLGMPFYFDQDINIKAGQAAGYAIGLDYRTISK 417
            ||.|:|.||..|.|:.|||..|:.||::|.:|::|:|.:.:|..||....|.|.|:.:::||:||
  Rat   359 PQNDLLGHPKTKAFVTHGGANGIYEAIHHGIPMIGIPLFGEQHDNIAHMVAKGAAVEVNFRTMSK 423

  Fly   418 DQLKSALHALLKDPKYQANMMKASRIFRDRPLGAMDTAMYWINYVVEHRGAPHLVAAGVHLPWYQ 482
            ..:.:||..::.:|.|:.|.|..|.|..|:|...:|.|::||.:|:.|:||.||.:.|.:|||||
  Rat   424 SDMLNALEEVINNPFYKKNAMWLSTIHHDQPTKPLDRAVFWIEFVMRHKGAKHLRSLGHNLPWYQ 488

  Fly   483 FYLLDVSAIIL---AITLLPLLTLYAVSRNYKSFRGIRAQKKEAKTE 526
            ::.|||...:|   |:|:  :|.|......|:.|     .|||.||:
  Rat   489 YHSLDVIGFLLTCVAVTV--VLALKCFLFVYRFF-----VKKEKKTK 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B2	NP_001097859.4	Glycosyltransferase_GTB-type	31..497	CDD:471961	161/506 (32%)
Ugt2b35	NP_001004271.1	UDPGT	24..527	CDD:278624	171/547 (31%)