Protein Alignment Ugt49B2 and ugt2a6

DIOPT Version :9

• Sequence 1: NP_001097859.4
• Gene: Ugt49B2 / 42538
• FlyBaseID: FBgn0038886
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001138283.1
• Gene: ugt2a6 / 797211
• ZFINID: ZDB-GENE-081104-3
• Length: 529
• Species: Danio rerio
• Alignment Length: 571
• Identity: 156/571 - (27%)
• Similarity: 262/571 - (45%)
• Gaps: 101/571 - (17%)

  Fly     8 LFVCLL----GTGDGARILAPFFLPVK-SHFMMTDAIIRELVKRGHEVTFITPLS------LAKE 61
            |.||||    ..|...|:|.   :|.: ||:.....:|..||.:.|.||.:...|      ..||
Zfish     6 LLVCLLLCGVDVGWSGRVLV---MPGEYSHWHNMRPVIEALVDKNHSVTVLVGSSSPTVPHTQKE 67

  Fly    62 NLGPNYREILLPK----------YDTWAD--ISAMMKTKSALDMIDMSKLTHMRLAQHIGIKSTD 114
            ....:..::.:.|          ::.|.:  ||...||.....::.:.:
Zfish    68 RFEYHVFKVNMEKEVVDYLWIHFHELWMNETISTYEKTLEVWQLMSLFR---------------- 116

  Fly   115 FALAHPEVQELIYAKDKKGKFDLLLVEQFHNEG------------ALMLGYIYEIPAITIATFAY 167
               ||.|  ||:     ||.||:.|::...:..            :.::.....||.:.....::
Zfish   117 ---AHSE--ELV-----KGLFDVGLLKTLRDSNYDVLFSDLTMPFSDLMAQKLNIPHVLSMRISF 171

  Fly   168 ANYFSQVFGFVN-PLSYVPNVFLS--CTDRMSLWERLENVVI-------------STAEDVVREV 216
            |:...::.|.:. |.||||.....  .|||||..||:||:::             .|.:.:..|:
Zfish   172 ASALERLCGQMPVPQSYVPAAVAQGHLTDRMSFTERVENMLLYITHTAMFQLTTKFTFDHIYAEI 236

  Fly   217 SYYPQQDAVIRKHFSSLLPRVPTVKQLEQNISVILLNSYMPLTSPRPMSQNMISVGGLHILPPKP 281
            |..|                 .|:.:......:.|:.:|.....|||...|...||||...|.||
Zfish   237 SGEP-----------------TTMCETIGKTDIWLIRTYWDFEYPRPFPPNFKFVGGLQCKPAKP 284

  Fly   282 LPEHIKNYLDNA-EHGAIYFSLGSQVRSADMPAEKLQIFLDVFASLKQRVLWKFEDDQLPNLPDN 345
            |.:.::.::.:: :||.:.|||||.::  ::..:|..........:.|:|:|::.......|..|
Zfish   285 LAKELEEFVQSSGDHGIVVFSLGSMIK--NLTVQKANTIAAALGQISQKVVWRYSGKTPETLAPN 347

  Fly   346 VKVEKWLPQADILAHPNVKVFIAHGGLFGMQEAVYHAVPVLGMPFYFDQDINIKAGQAAGYAIGL 410
            .|:..|:||.|:|.||..|.||.|||..|:.||:||.||::|:|.:.||..|:...::.|.|:.|
Zfish   348 TKIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQPDNLMHLKSKGAAVVL 412

  Fly   411 DYRTISKDQLKSALHALLKDPKYQANMMKASRIFRDRPLGAMDTAMYWINYVVEHRGAPHLVAAG 475
            |:.|:....|..||..:|.:|.|:.::|:.|||..|:|:..:|.|:|||.:|:.::||.||....
Zfish   413 DFFTLESKDLVDALKTVLNNPSYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQA 477

  Fly   476 VHLPWYQFYLLDVSAIILAITLLPLLTLYAVSRNYKSFRGIRAQKKEAKTE 526
            ..|.|||::.|||:|.:|:||.| :..|:..:..:...|.:|..:.|.|::
Zfish   478 HELSWYQYHCLDVAAFLLSITAL-ITFLWVKACCFLFRRCVRKTRPERKSK 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B2	NP_001097859.4	egt	1..502	CDD:223071	151/545 (28%)
		UDPGT	31..497	CDD:278624	140/512 (27%)
ugt2a6	NP_001138283.1	UDPGT	21..519	CDD:278624	147/546 (27%)
		egt	<254..485	CDD:223071	83/232 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170585276
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930