Protein Alignment Ugt49B2 and Ugt2a1

DIOPT Version :10

• Sequence 1: NP_001097859.4
• Gene: Ugt49B2 / 42538
• FlyBaseID: FBgn0038886
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_063129643.1
• Gene: Ugt2a1 / 63867
• RGDID: 69432
• Length: 737
• Species: Rattus norvegicus
• Alignment Length: 487
• Identity: 155/487 - (31%)
• Similarity: 254/487 - (52%)
• Gaps: 43/487 - (8%)

  Fly    31 SHFMMTDAIIRELVKRGHEVTFITPLSLAKENLGP----NYREILLPKYDTWADISAMMKTKSAL 91
            ||::....::.|||:|.|.||.:........|..|    ::.||  |...|.:.|..|::...||
  Rat   241 SHWLNIKILLEELVQRNHSVTVLAASETLFINSSPDAFISFEEI--PVSYTRSKIDEMIEHMIAL 303

  Fly    92 DMID--MSKLTHMRLAQHIGIKSTDFALAHPEV------QELIYAKDKKGKFDLLLVEQFHNEG- 147
             .:|  .:.||.....:.:|.....|...:.::      ...:.|:.:||.||:|:.:.....|
  Rat   304 -WLDHRPTPLTMWAFYKELGKLFAAFYKINKQICDGVLKNATLMARLQKGGFDVLISDPVTMCGE 367

  Fly   148 --ALMLGYIYEIPAITIATFAYANYFSQVF------GFV-NPLSYVPNVFLSCTDRMSLWERLEN 203
              ||.||    ||      |.|...||..|      |.: .|:||||......||:|:..||::|
  Rat   368 LVALKLG----IP------FVYTLRFSPAFTVERHCGKIPTPVSYVPAALSELTDQMTFGERVKN 422

  Fly   204 VVISTAEDVVREVSYYPQQDAVIRKHFSSLLPRVPTVKQLEQNISVILLNSYMPLTSPRPMSQNM 268
            .:..:.:|.:.: ||:.:.::    ::|.:|.|..|:.:......:.|:.:|.....|||...|.
  Rat   423 TISYSLQDYIFK-SYWGEWNS----YYSRVLGRPTTLCETMGKAEIWLMRTYWDFEFPRPYLPNF 482

  Fly   269 ISVGGLHILPPKPLPEHIKNYLD-NAEHGAIYFSLGSQVRSADMPAEKLQIFLDVFASLKQRVLW 332
            ..|||||..|.||||:.::.::. :.|||.:.|||||.|:  ::..||..:.....|.:.|:|||
  Rat   483 EFVGGLHCKPAKPLPKEMEEFVQTSGEHGVVVFSLGSMVK--NLTEEKANLIASALAQIPQKVLW 545

  Fly   333 KFEDDQLPNLPDNVKVEKWLPQADILAHPNVKVFIAHGGLFGMQEAVYHAVPVLGMPFYFDQDIN 397
            :::......|..|.::..|:||.|:|.||..:.||.|||..|:.||:||.:|::|:|.:.||..|
  Rat   546 RYKGKIPATLGSNTRLFDWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPMVGVPMFADQPDN 610

  Fly   398 IKAGQAAGYAIGLDYRTISKDQLKSALHALLKDPKYQANMMKASRIFRDRPLGAMDTAMYWINYV 462
            |...:|.|.|:.::..|::...|.||:.|::.:|.|:.|.|:.|||..|:|:..:|.|::||.:|
  Rat   611 IAHMKAKGAAVEVNMNTMTSADLLSAVRAVINEPFYKENAMRLSRIHHDQPVKPLDRAVFWIEFV 675

  Fly   463 VEHRGAPHLVAAGVHLPWYQFYLLDVSAIILA 494
            :.|:||.||..|...|.|:|::.|||...:||
  Rat   676 MRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLA 707

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B2	NP_001097859.4	Glycosyltransferase_GTB-type	31..497	CDD:471961	155/487 (32%)
Ugt2a1	XP_063129643.1	None