Protein Alignment Ugt49B2 and Ugt2a2

DIOPT Version :9

• Sequence 1: NP_001097859.4
• Gene: Ugt49B2 / 42538
• FlyBaseID: FBgn0038886
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001019319.1
• Gene: Ugt2a2 / 552899
• MGIID: 3576095
• Length: 528
• Species: Mus musculus
• Alignment Length: 503
• Identity: 161/503 - (32%)
• Similarity: 259/503 - (51%)
• Gaps: 61/503 - (12%)

  Fly    31 SHFMMTDAIIRELVKRGHEVTFITPLSLAKENLGPNYREILLPKYDTWADISAMMKTKSALD--- 92
            ||::....::.|||:|.|.||.:.|    .|.|..|.|   |..:..:.:| .:..|||.:|
Mouse    32 SHWLNIKILLEELVQRNHSVTVLAP----SETLFINSR---LDAFINFEEI-PVSYTKSKIDEII 88

  Fly    93 --MIDM------SKLTHMRLAQHIG-IKST---------DFALAHPEVQELIYAKDKKGKFDLLL 139
              ||.:      :.||.....:.:| :.:|         |..|.:|.|.|.:    :||.||:||
Mouse    89 EHMIALWLDHRPTPLTMWTFYKELGNLLATFYTTNKQMCDGVLNNPTVMERL----QKGGFDVLL 149

  Fly   140 VEQFHNEG---ALMLGYIYEIPAITIATFAYANYFSQVFGFVN-------PLSYVPNVFLSCTDR 194
            .:.....|   ||.||    ||      |.|...||..|....       |:||||......||:
Mouse   150 ADPVTMCGELVALKLG----IP------FVYTLRFSPAFTVERHCGKIPAPISYVPAALSELTDQ 204

  Fly   195 MSLWERLENVVISTAEDVVREVSYYPQQDAVIRKHFSSLLPRVPTVKQLEQNISVILLNSYMPLT 259
            ||..||::|::..:.:|.:.: :|:.:.::    ::|.:|.|..|:.:......:.|:.:|....
Mouse   205 MSFGERVKNIISYSLQDYIFK-TYWGEWNS----YYSKVLGRPTTLCETMGKAEIWLMRTYWDFE 264

  Fly   260 SPRPMSQNMISVGGLHILPPKPLPEHIKNYLD-NAEHGAIYFSLGSQVRSADMPAEKLQIFLDVF 323
            .|||...|...|||||..|.||||:.::.::. :.|||.:.|||||.|:  ::..||..:.....
Mouse   265 FPRPYLPNFEFVGGLHCKPAKPLPKEMEEFVQTSGEHGIVVFSLGSMVK--NLTDEKANLIASAL 327

  Fly   324 ASLKQRVLWKFEDDQLPNLPDNVKVEKWLPQADILAHPNVKVFIAHGGLFGMQEAVYHAVPVLGM 388
            |.:.|:|||:::......|..|.::..|:||.|:|.||..:.||.|||..|:.||:||.:|::|:
Mouse   328 AQIPQKVLWRYKGKIPDTLGSNTRLFDWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPMVGV 392

  Fly   389 PFYFDQDINIKAGQAAGYAIGLDYRTISKDQLKSALHALLKDPKYQANMMKASRIFRDRPLGAMD 453
            |.:.||..||...:|.|.|:.::..|::...|.:||..::.:|.|:.|.|:.|||..|:|:..:|
Mouse   393 PMFADQPDNIAHMKAKGAAVEVNMNTMTSSDLLNALRTVINEPSYKENAMRLSRIHHDQPVKPLD 457

  Fly   454 TAMYWINYVVEHRGAPHLVAAGVHLPWYQFYLLDVSAIILAITLLPLL 501
            .|::||.:|:.|:||.||..|...|.|:|::.|||...:||.....:|
Mouse   458 RAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLACVASAIL 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B2	NP_001097859.4	egt	1..502	CDD:223071	161/503 (32%)
		UDPGT	31..497	CDD:278624	160/497 (32%)
Ugt2a2	NP_001019319.1	UDPGT	22..516	CDD:278624	161/503 (32%)
		egt	<267..487	CDD:223071	84/221 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840268
Domainoid	1	1.000	259	1.000	Domainoid score	I1975
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2975
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm42461
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.790