Protein Alignment Ugt49B2 and Ugt37A3

DIOPT Version :10

• Sequence 1: NP_001097859.4
• Gene: Ugt49B2 / 42538
• FlyBaseID: FBgn0038886
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Alignment Length: 541
• Identity: 159/541 - (29%)
• Similarity: 265/541 - (48%)
• Gaps: 43/541 - (7%)

  Fly     3 LFMKLLFVCLLGTGDGARILAPFFLPVKSHFMMTDAIIRELVKRGHEVTFITPLSLAKENLGPNY 67
            |.:.:....::|:..||.||..|.....||.::..:..:.|.:.||.||.:|.|.....:.....
  Fly     9 LLLAIAIGAVMGSSQGANILGLFPSLSPSHLIIQMSAAKVLAENGHNVTVVTVLKPVVNHKNITV 73

  Fly    68 REILLPKYDTWADISAMMKTKSALDMIDMSK--LTHMRLAQHIG--IKSTDFALAHPEVQELIYA 128
            .::.|.|    .:...|..|..|:...|.|.  |:.:|::..:.  |:.....|.:..|::|..
  Fly    74 IQVPLSK----EEAQQMSDTIGAMSKNDNSNMALSLLRMSDQMDFMIRKNAETLMNDRVRDLYL- 133

  Fly   129 KDKKGKFDLLLVEQFHNEGALMLGYIYEI--PAITIATFAYANYFSQVFGFVNPL--SY--VPNV 187
             ::..||||::...|.|:  ..||:..::  |.|.:||....:..:.:.|  |||  ||  :.|.
  Fly   134 -NRGNKFDLVISGYFMND--FQLGFARKVNAPVIVLATMPPNHLLNPLIG--NPLEVSYAGISNP 193

  Fly   188 FLSCTDRMSLWERLENVVISTAEDVVREVS------YYPQQDAVIRKHFSSLLPRVPTVKQLEQN 246
             ...:..::...||.:.:.|....|...:|      :|        |......|::|...::.:|
  Fly   194 -AEGSKAVTFQRRLSSYMQSLGFGVFSHLSERRNRNWY--------KEVYGNDPKMPEYSEMLKN 249

  Fly   247 ISVILLNSYMPLTSP-RPMSQNMISVGGLHIL-PPKPLPEHIKNYLDNAEHGAIYFSLGSQVRSA 309
            .|::..:|:.....| ||...:.|.:||:.|. .|.|||::|..:|.||..|||..||||.|:..
  Fly   250 TSLVFFSSHAASEGPIRPNVPSAIEIGGIQIKDKPDPLPQNIAEFLGNATDGAILLSLGSNVQGK 314

  Fly   310 DMPAEKLQIFLDVFASLKQRVLWKFED-DQLPNLPDNVKVEKWLPQADILAHPNVKVFIAHGGLF 373
            .:..:.:....:|.:.||:||:||:|| :..|....|:...|||||.|||||||:|:||.|.|..
  Fly   315 HLNPDTVAKMFNVLSKLKERVIWKWEDQENTPGKSANILYSKWLPQDDILAHPNIKLFINHAGKG 379

  Fly   374 GMQEAVYHAVPVLGMPFYFDQDINIKAGQAAGYAIGLDYRTISKDQLKSALHALLKDPKYQANMM 438
            |:.|:.||..|:|.:|.:.||..|..|...:|:.:.|...|:.:...:.|:..:|.:|:|...:.
  Fly   380 GITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLTLEEKPFQEAILEILSNPQYAERVK 444

  Fly   439 KASRIFRDRPLGAMDTAMYWINYVVEHRGAPHLVAAGVHLPWYQFYLLDVSAIILAITLLPLLTL 503
            ..|.::||||:.|.::.:||..||:.|.||.||.:..||:.:.....:|:..:|..| |:.:|.|
  Fly   445 SFSTLYRDRPMTARESFLYWTEYVIRHHGAAHLQSPLVHMSFIAANNIDICFLIFVI-LVSVLVL 508

  Fly   504 --YAVSRNYKSFRGIRAQKKE 522
              :.|...|:.|  |...|||
  Fly   509 IKFLVQFIYRRF--ISKPKKE 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B2	NP_001097859.4	Glycosyltransferase_GTB-type	31..497	CDD:471961	142/484 (29%)
Ugt37A3	NP_650229.2	GT1_Gtf-like	25..464	CDD:340817	132/457 (29%)