Protein Alignment Ugt49B2 and ugt1ab

DIOPT Version :9

• Sequence 1: NP_001097859.4
• Gene: Ugt49B2 / 42538
• FlyBaseID: FBgn0038886
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_998587.2
• Gene: ugt1ab / 406731
• ZFINID: ZDB-GENE-040426-2762
• Length: 536
• Species: Danio rerio
• Alignment Length: 569
• Identity: 155/569 - (27%)
• Similarity: 267/569 - (46%)
• Gaps: 98/569 - (17%)

  Fly     3 LFMKLL----FVCLLGTG--DGARILAPFFLPVK-SHFMMTDAIIRELVKRGHEVTFITPLSLAK 60
            ||:..|    |:||..:.  ...::|.   :||. ||::....::.|:..||||:..:.|.:
Zfish    15 LFVPALGLFAFLCLFSSESVQAGKVLV---MPVDGSHWLSMKILVEEMSSRGHEMVVLVPET--- 73

  Fly    61 ENLGPNYREILLPKYDTWADIS--------------------AMMKTKSALDMI----DMSKLTH 101
                    .||:.|...:...|                    |:.|....:|::    ::.:.|:
Zfish    74 --------SILIGKSGNFTTKSFRVPYSFDELNAHVDHIRKTAIEKAPRFIDIVGALGNLIQFTN 130

  Fly   102 MRLAQHIGIKSTDFALAHPEVQELIYAKDKKGKFDLLLVEQFHNEGALMLGYIYEIPAITIATFA 166
            |::....|:...:     |.::.|     :..|||.||.:.|...|:::..| :.|||:
Zfish   131 MQVKACEGLLYDE-----PLMKSL-----RDMKFDALLTDPFLPCGSVIADY-FSIPAV------ 178

  Fly   167 YANYFSQVFGF-----------VNPLSYVPNVFLSCTDRMSLWERLENVVISTAEDVVREVSYYP 220
               ||.:  |.           .:|.|::|..|...||:|:..:|:.|..::..|..:....:..
Zfish   179 ---YFLR--GIPCRLDEAAAQCPSPPSFIPRFFTGYTDKMTFPQRMINTFMTVFEKYLCHQLFAS 238

  Fly   221 QQDAVIRKHFSSLLPRVPTVKQLEQNISVILLNSYMPLTSPRPMSQNMISVGGLHILPPKPLPEH 285
            ..:...|     .|.:..:..:|..:.:|.||........|:|...||:.:||::.....||.:.
Zfish   239 FDELATR-----YLKKDTSYAELLGHGAVWLLRYDFSFEYPKPQMPNMVQIGGINCAKRAPLTKE 298

  Fly   286 IKNYLD-NAEHGAIYFSLGSQVRSADMPAEKLQIFLDVFASLKQRVLWKFEDDQLPNLPDNVKVE 349
            ::.::: :.|||.:.|:|||.|  :.:|..|.:.|.:.|..:.|||||::......|.|.|||:.
Zfish   299 LEEFVNGSGEHGFVVFTLGSMV--SQLPEAKAREFFEAFRQIPQRVLWRYTGPVPENAPKNVKLM 361

  Fly   350 KWLPQADILAHPNVKVFIAHGGLFGMQEAVYHAVPVLGMPFYFDQDINIKAGQAAGYAIGLDYRT 414
            |||||.|:|.||.|:.|:.|||..|:.|.:.:.||::.:|.:.||..|.:...:.|.|..|....
Zfish   362 KWLPQNDLLGHPKVRAFVTHGGSHGIYEGICNGVPMVMLPLFGDQGDNAQRLVSRGVAESLTIYD 426

  Fly   415 ISKDQLKSALHALLKDPKYQANMMKASRIFRDRPLGAMDTAMYWINYVVEHRGAPHLVAAGVHLP 479
            ::.::|..||..::.|..|:..|||.|.|.||||:..:|.|::|..:|:.|:||.||..|...|.
Zfish   427 VTSEKLLVALKKVINDKSYKEKMMKLSAIHRDRPIEPLDLAVFWTEFVMRHKGAEHLRPAAHDLN 491

  Fly   480 WYQFYLLDVSAIILAITLLPLLTLYAVSRN------YKSFRGIRAQKKE 522
            |.|::.|||...:|.|    |||:..|:..      .|.|:  ::|||:
Zfish   492 WIQYHSLDVIGFLLLI----LLTVIFVTVKSCMFCFRKCFK--KSQKKK 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B2	NP_001097859.4	egt	1..502	CDD:223071	147/541 (27%)
		UDPGT	31..497	CDD:278624	137/501 (27%)
ugt1ab	NP_998587.2	UDPGT	37..524	CDD:278624	144/533 (27%)
		egt	<279..513	CDD:223071	88/239 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	252	1.000	Domainoid score	I2043
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I3189
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.860