Protein Alignment Ugt49B2 and Ugt1a3

DIOPT Version :10

• Sequence 1: NP_001097859.4
• Gene: Ugt49B2 / 42538
• FlyBaseID: FBgn0038886
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_958827.1
• Gene: Ugt1a3 / 396551
• RGDID: 1549728
• Length: 531
• Species: Rattus norvegicus
• Alignment Length: 547
• Identity: 162/547 - (29%)
• Similarity: 269/547 - (49%)
• Gaps: 58/547 - (10%)

  Fly     7 LLFVCLLGTGDGARILAPFFLPVK-SHFMMTDAIIRELVKRGH-------EVT-------FIT-- 54
            ||.:|.|...:|.::|.   .|:: ||::....::|||..|||       |||       |.|
  Rat    14 LLLLCALPWAEGGKVLV---FPMEGSHWLSMRDVVRELHARGHQAVVLAPEVTVHIKEEDFFTLQ 75

  Fly    55 --PLSLAKENLGPNYREILLPK----YDTWADISAMMKTKSALDMIDMSKLTHMRLAQHIGIKST 113
              |:...||    .||..||..    ::|...:..:::..:|::.:....:...|...|
  Rat    76 TYPVPYTKE----EYRHHLLGHLQNFFETEFSLKLVLQRMAAVNNVSTFYVRSCRGLLH------ 130

  Fly   114 DFALAHPEVQELIYAKDKKGKFDLLLVEQFHNEGALMLGYIYEIPAITIATFAYANYFSQVFGFV 178
            :.||    :|.|     ....||::|.:.|...||::..|: .:||:............:.....
  Rat   131 NTAL----IQSL-----NSSSFDVVLTDPFFPCGAVLAMYL-RVPAVFFLQSMLCELEFEATNSP 185

  Fly   179 NPLSYVPNVFLSCTDRMSLWERLENVVISTAEDVVREVSYYPQQDAVIRKHFSSLLPRVPTVKQL 243
            ||.||:|.:....:|.||..:|::|::.......:..|:|     ..:.:..|.||.|..:|.::
  Rat   186 NPSSYIPRLLTLNSDHMSFLDRVKNMLYPVPWMYLCHVNY-----GSLARLASDLLQREVSVVEI 245

  Fly   244 EQNISVILLNSYMPLTSPRPMSQNMISVGGLHILPPKPLPEHIKNYLD-NAEHGAIYFSLGSQVR 307
            .::.||.||........|||...||:.:||::....|||.:..:.|:: :.|||.:.|||||.|
  Rat   246 LRHASVWLLRKDFVFYYPRPFMPNMVFIGGINCANRKPLSQEFEAYVNASGEHGIVVFSLGSMV- 309

  Fly   308 SADMPAEKLQIFLDVFASLKQRVLWKFEDDQLPNLPDNVKVEKWLPQADILAHPNVKVFIAHGGL 372
             :::|.:|.....:....:.|.|||::...:..||..|..:.|||||.|:|.||..:.||.|.|.
  Rat   310 -SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGS 373

  Fly   373 FGMQEAVYHAVPVLGMPFYFDQDINIKAGQAAGYAIGLDYRTISKDQLKSALHALLKDPKYQANM 437
            .|:.|.:.:.||::.||.:.||..|.|..:..|..:.|:...::.|.|::||..::.:..|:.|:
  Rat   374 HGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENI 438

  Fly   438 MKASRIFRDRPLGAMDTAMYWINYVVEHRGAPHLVAAGVHLPWYQFYLLDVSAIILAITLLPLLT 502
            |:.|.:.:|||:..:|.|::|:.||:.|:|||||..|...|.|||::.|||...:|||.|..:..
  Rat   439 MRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFI 503

  Fly   503 LYAVSRNY---KSFRGIRAQKKEAKTE 526
            :|. |..|   |.|.|....||..|::
  Rat   504 VYK-SCAYGCRKCFGGKGRVKKSHKSK 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B2	NP_001097859.4	Glycosyltransferase_GTB-type	31..497	CDD:471961	145/488 (30%)
Ugt1a3	NP_958827.1	UDPGT	26..522	CDD:278624	154/526 (29%)