Protein Alignment Ugt49B2 and Ugt1a10

DIOPT Version :9

• Sequence 1: NP_001097859.4
• Gene: Ugt49B2 / 42538
• FlyBaseID: FBgn0038886
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_964003.2
• Gene: Ugt1a10 / 394430
• MGIID: 3580642
• Length: 530
• Species: Mus musculus
• Alignment Length: 564
• Identity: 163/564 - (28%)
• Similarity: 264/564 - (46%)
• Gaps: 92/564 - (16%)

  Fly     8 LFVCLL---GTGDGARILAPFFLPVK-SHFMMTDAIIRELVKRGHEVTFITP------------- 55
            |.||||   |.....|:|.   :|:. ||:.....::.:|::|||||..:.|
Mouse    12 LCVCLLLASGLVQAGRLLV---VPMDGSHWFDMQMVVEKLIQRGHEVVVVIPEVSWRLGKSLNCT 73

  Fly    56 -----LSLAKENLGPNYREILLPKYDTW----ADISAMMKTKSALDMIDMSKLTHMR-------L 104
                 :|...|:|.   ||.....|..|    ..|.:.| |.||....:: ..:|.|       |
Mouse    74 VKTYSVSHTLEDLD---REFKYFTYTQWKTPEQSIRSFM-TGSARGFFEL-MFSHSRGLFNDKKL 133

  Fly   105 AQHIGIKSTDFALAHPEVQELIYAKDKKGKFDLLLVEQFHNEGALMLGYIYEIPAITIATFAYAN 169
            .:::                      |:..||.:.::.|...|.::..|: .:|::..|..::..
Mouse   134 VEYL----------------------KQRSFDAVFLDPFDVCGLIVAKYL-SLPSVIFARLSFCY 175

  Fly   170 YFSQVFGFVNPLSYVPNVFLSCTDRMSLWERLENVVISTAEDVVREVSYYPQQDAVIRKHF---- 230
            |..:.....:.|||||.:|...||.|:..||:.|             .|...:|.|...:|
Mouse   176 YLEEGAQCPSLLSYVPRLFSKYTDTMTFKERVWN-------------HYMYIEDYVFCPYFFKTA 227

  Fly   231 ----SSLLPRVPTVKQLEQNISVILLNSYMPLTSPRPMSQNMISVGGLHILPPKPLPEHIKNYLD 291
                |.:|....|:..|...:|:.||.:...|..|||:..||:.|||::.|..|||.:..:.|::
Mouse   228 VEIASEVLQTPVTMTDLFSPVSIWLLRTDFVLEFPRPVMPNMVFVGGMNCLQGKPLSKEFEAYVN 292

  Fly   292 -NAEHGAIYFSLGSQVRSADMPAEKLQIFLDVFASLKQRVLWKFEDDQLPNLPDNVKVEKWLPQA 355
             :.|||.:.|||||.|  :::|.:|.....:....:.|.|||::...:..||..|..:.|||||.
Mouse   293 ASGEHGIVVFSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQN 355

  Fly   356 DILAHPNVKVFIAHGGLFGMQEAVYHAVPVLGMPFYFDQDINIKAGQAAGYAIGLDYRTISKDQL 420
            |:|.||..:.||.|.|..|:.|.:.:.||::.||.:.||..|.|..:..|..:.|:...::.|.|
Mouse   356 DLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDL 420

  Fly   421 KSALHALLKDPKYQANMMKASRIFRDRPLGAMDTAMYWINYVVEHRGAPHLVAAGVHLPWYQFYL 485
            ::||..::.:..|:.|:|:.|.:.:|||:..:|.|::|:.||:.|:|||||..|...|.|||::.
Mouse   421 ENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHS 485

  Fly   486 LDVSAIILAITLLPLLTLYAVSRNY---KSFRGIRAQKKEAKTE 526
            |||...:|||.|..:..::.... |   |.|.|....||..|::
Mouse   486 LDVIGFLLAIVLTVVFIVFKCCA-YGCRKCFGGKGRVKKSHKSK 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B2	NP_001097859.4	egt	1..502	CDD:223071	156/535 (29%)
		UDPGT	31..497	CDD:278624	146/503 (29%)
Ugt1a10	NP_964003.2	egt	14..502	CDD:223071	155/533 (29%)
		UDPGT	26..521	CDD:278624	154/541 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840766
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830