Protein Alignment Ugt49B2 and Ugt2a3

DIOPT Version :10

• Sequence 1: NP_001097859.4
• Gene: Ugt49B2 / 42538
• FlyBaseID: FBgn0038886
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001129341.1
• Gene: Ugt2a3 / 289533
• RGDID: 1308444
• Length: 534
• Species: Rattus norvegicus
• Alignment Length: 531
• Identity: 159/531 - (29%)
• Similarity: 265/531 - (49%)
• Gaps: 68/531 - (12%)

  Fly     7 LLFVCLLGTGDGARILA-PFFLPVKSHFMMTDAIIRELVKRGHEVTF------------ITPLSL 58
            ||.:|..|.|..:::|. |..:   ||::....|:.||..||||||.            :|||..
  Rat    12 LLQLCWSGCGICSKVLVWPCDM---SHWLNLKTILEELAARGHEVTVLKYPSIIIDQSKLTPLQF 73

  Fly    59 AKENLGPNY---------REI------LLPKYDTWADISAMMKTKSALDMIDMSKLTHMRLAQHI 108
              ||:...|         .||      ::|....|         ::|..:.|.    .::|..:.
  Rat    74 --ENIPVLYETEVAENHLNEIVNLAVNVIPNLSLW---------EAARTLQDF----FLQLTGNF 123

  Fly   109 G--IKSTDFALAHPEVQELIYAKDKKGKFDLLLVEQFHNEGALMLGYIYEIPAITIATFAYANYF 171
            .  .:||.:       .:.:..|.:..|:|:::::.....|.| :..:.:||.:....|:.....
  Rat   124 EDLCRSTLY-------NQTLMNKLRDAKYDVMVLDPVIPCGEL-VAEVLQIPFVNTLRFSMGYSM 180

  Fly   172 SQVFGFVN-PLSYVPNVFLSCTDRMSLWERLENVVISTAEDVVREVSYYPQQD-AVIRKHFSSLL 234
            .:..|.:. ||||||.|....||.|:..||::|:::|...:.     :..|.| |...:.:|..|
  Rat   181 EKYCGQLPVPLSYVPVVMGELTDHMTFTERVKNMMLSLFFEF-----WLQQYDFAFWDQFYSKTL 240

  Fly   235 PRVPTVKQLEQNISVILLNSYMPLTSPRPMSQNMISVGGLHILPPKPLPEHIKNYLDNA-EHGAI 298
            .|..|..:......:.|:.:|..:..|||...|...|||||..|.||||:.::.::.:: |||.:
  Rat   241 GRPTTFCKTVGKAEIWLIRTYWDIEFPRPYLPNFEFVGGLHCKPAKPLPKELEEFVQSSGEHGVV 305

  Fly   299 YFSLGSQVRSADMPAEKLQIFLDVFASLKQRVLWKFEDDQLPNLPDNVKVEKWLPQADILAHPNV 363
            .|||||.::  ::..||..:.....|.:.|:|||::...:...|..|.::..|:||.|:|.||..
  Rat   306 VFSLGSMIK--NLTEEKANLIASALAQIPQKVLWRYSGKKPATLGPNTRILNWIPQNDLLGHPKT 368

  Fly   364 KVFIAHGGLFGMQEAVYHAVPVLGMPFYFDQDINIKAGQAAGYAIGLDYRTISKDQLKSALHALL 428
            :.||.|||..|:.||:||.||::|:|.:.||..||...:|.|.|:.:...|::...|.|||.|::
  Rat   369 RAFITHGGTNGIYEAIYHGVPMVGIPMFGDQPYNIAHMEAKGAAVKVAINTMTSADLLSALRAVI 433

  Fly   429 KDPKYQANMMKASRIFRDRPLGAMDTAMYWINYVVEHRGAPHLVAAGVHLPWYQFYLLDVSAIIL 493
            .:|.|:.|.|:.||:..|:|:..:|.|::||.:|:.|:||.||..|...|.|:|::.|||...:|
  Rat   434 NEPSYKENAMRLSRVHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLL 498

  Fly   494 --AITLLPLLT 502
              .:||..::|
  Rat   499 VCVVTLTFVIT 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B2	NP_001097859.4	Glycosyltransferase_GTB-type	31..497	CDD:471961	149/499 (30%)
Ugt2a3	NP_001129341.1	UDPGT	25..519	CDD:278624	154/518 (30%)