Protein Alignment Ugt49B2 and Ugt2b15

DIOPT Version :9

• Sequence 1: NP_001097859.4
• Gene: Ugt49B2 / 42538
• FlyBaseID: FBgn0038886
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_695226.3
• Gene: Ugt2b15 / 266685
• RGDID: 628623
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 550
• Identity: 170/550 - (30%)
• Similarity: 272/550 - (49%)
• Gaps: 78/550 - (14%)

  Fly    11 CLLGTGDGARILAPFFLPVK-SHFMMTDAIIRELVKRGHEVTFIT-------------------- 54
            |...:|:..::|.   .|:: ||:|....|:.|||:||||||.:.
  Rat    16 CCFQSGNCGKVLV---WPMEFSHWMNIKTILDELVQRGHEVTVLKPSAYYVLDPKKSPDLKFETF 77

  Fly    55 PLSLAKENLGPNYREILLPKYDTWADISAMMKTKSALDMIDMSKLTHMRLAQHI--GIKSTDFAL 117
            |.|::|:.| .||   .:...|.|           ..::...:.|::..|.|::  |......:|
  Rat    78 PTSVSKDEL-ENY---FIKLVDVW-----------TYELQRDTCLSYSPLLQNMIDGFSDYYLSL 127

  Fly   118 AHPEV-QELIYAKDKKGKFDLLLVEQFHNEGALMLGYIYEIPAITIATFAYANYFSQVF------ 175
            ....| .:.:.||.::.|||:||.:.....|.| :..:..||      |.|:..||..:
  Rat   128 CKDTVSNKQLMAKLQESKFDVLLSDPVAACGEL-IAEVLHIP------FLYSLRFSPGYKIEKSS 185

  Fly   176 -GFVNPLSYVPNVFLSCTDRMSLWERLENVVISTAEDVVREVSYYPQQDAVIRKHFSSLLPRVPT 239
             .|:.|.||||.:.......|:..:|::|::.:...|....:....:.|    ..:|.:|.|..|
  Rat   186 GRFILPPSYVPVILSGMGGPMTFIDRVKNMICTLYFDFWFHMFNAKKWD----PFYSEILGRPTT 246

  Fly   240 VKQLEQNISVILLNSYMPLTSPRPMSQNMISVGGLHILPPKPLPEHIKNYLDNA-EHGAIYFSLG 303
            :.:......:.|:.||..|..|.|...|:..:|||...||||||:.:::::.:: |||.:.||||
  Rat   247 LAETMGKAEMWLIRSYWDLEFPHPTLPNVDYIGGLQCRPPKPLPKDMEDFVQSSGEHGVVVFSLG 311

  Fly   304 SQVRSADMPAEKLQIFLDVFASLKQRVLWKFEDDQLPNLPDNVKVEKWLPQADILAHPNVKVFIA 368
            |.|.|  |..||........|.:.|:|||||:......|..|.:|.|||||.|:|.||..|.|:.
  Rat   312 SMVSS--MTEEKANAIAWALAQIPQKVLWKFDGKTPATLGPNTRVYKWLPQNDLLGHPKTKAFVT 374

  Fly   369 HGGLFGMQEAVYHAVPVLGMPFYFDQDINIKAGQAAGYAIGLDYRTISKDQLKSALHALLKDPKY 433
            |||..|:.||:||.:|::|:|.:.:|..||....|.|.|:.|:.||:||..|.:||..::.:|.|
  Rat   375 HGGANGVYEAIYHGIPMVGIPMFGEQHDNIAHMVAKGAAVTLNIRTMSKSDLFNALKEIINNPFY 439

  Fly   434 QANMMKASRIFRDRPLGAMDTAMYWINYVVEHRGAPHLVAAGVHLPWYQFYLLDV-------SAI 491
            :.|.:..|.|..|:|:..:|.|::||.:|:.|:||.||...|.:|||||::.|||       ||:
  Rat   440 KKNAVWLSTIHHDQPMKPLDKAVFWIEFVMRHKGAKHLRPLGHNLPWYQYHSLDVIGFLLTCSAV 504

  Fly   492 ILAITLLPLLTLYAVSRNYKSFRGIRAQKK 521
            |..:|:...|.:|.:.        ::.:||
  Rat   505 IAVLTVKSFLFIYRLF--------VKKEKK 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B2	NP_001097859.4	egt	1..502	CDD:223071	166/529 (31%)
		UDPGT	31..497	CDD:278624	161/503 (32%)
Ugt2b15	NP_695226.3	UDPGT	24..527	CDD:278624	167/541 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344214
Domainoid	1	1.000	256	1.000	Domainoid score	I1959
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	275	1.000	Inparanoid score	I2882
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm9018
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.790