Protein Alignment Ugt49B2 and Ugt1a2

DIOPT Version :9

• Sequence 1: NP_001097859.4
• Gene: Ugt49B2 / 42538
• FlyBaseID: FBgn0038886
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_038729.1
• Gene: Ugt1a2 / 22236
• MGIID: 3576049
• Length: 533
• Species: Mus musculus
• Alignment Length: 552
• Identity: 160/552 - (28%)
• Similarity: 268/552 - (48%)
• Gaps: 68/552 - (12%)

  Fly     7 LLFVCLLGTGDGARILAPFFLPVK-SHFMMTDAIIRELVKRGH-------EVT-------FITPL 56
            ||.:|.|...:||::|.   ||:: |.::....::|||..|||       |||       |.|..
Mouse    16 LLLLCALPWAEGAKVLV---LPMEGSQWLSMRDVVRELHARGHQTVVLASEVTVHIKGEDFFTLK 77

  Fly    57 SLAKENLGPNYREILLPKYDTWADISAMMKTK-----------SALDMIDMSKLTHMRLAQHIGI 110
            :.|.......|::.:|      :||....||:           |..:..|:             .
Mouse    78 TYAFPYTKEEYQQEIL------SDIEKTFKTQHFVKAFFETTASIRNFFDL-------------Y 123

  Fly   111 KSTDFALAHPE--VQELIYAKDKKGKFDLLLVEQFHNEGALMLGYIYEIPAITIATFAYANYFSQ 173
            .::..||.|.:  :|:|     ....||::|.:.....||::..|: :|||:.|..........:
Mouse   124 SNSCIALLHNKMLIQQL-----NSSFFDVILTDPIFPCGAVLAKYL-QIPAVFILRSLSCGIEYE 182

  Fly   174 VFGFVNPLSYVPNVFLSCTDRMSLWERLENVVISTAEDVVREVSYYPQQDAVIRKHFSSLLPRVP 238
            .....||.||:||:....:|.|...:|::|::.......:..:|..|.:...     |.||.|..
Mouse   183 ATQCPNPSSYIPNLLTRLSDHMDFLQRVQNMLYYLVLKYICRLSITPYESLA-----SELLQREV 242

  Fly   239 TVKQLEQNISVILLNSYMPLTSPRPMSQNMISVGGLHILPPKPLPEHIKNYLD-NAEHGAIYFSL 302
            ::.::..:.||.|......|..|||:..||:.:||::.:..|||.:..:.|:: :.|||.:.|||
Mouse   243 SLVEVLSHASVWLFRGDFVLDYPRPIMPNMVFIGGINCVTKKPLSQEFEAYVNASGEHGIVVFSL 307

  Fly   303 GSQVRSADMPAEKLQIFLDVFASLKQRVLWKFEDDQLPNLPDNVKVEKWLPQADILAHPNVKVFI 367
            ||.|  :::|.:|.....:....:.|.|||::...:..||..|..:.|||||.|:|.||..:.||
Mouse   308 GSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFI 370

  Fly   368 AHGGLFGMQEAVYHAVPVLGMPFYFDQDINIKAGQAAGYAIGLDYRTISKDQLKSALHALLKDPK 432
            .|.|..|:.|.:.:.||::.||.:.||..|.|..:..|..:.|:...::.|.|::||..::.:..
Mouse   371 THSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKS 435

  Fly   433 YQANMMKASRIFRDRPLGAMDTAMYWINYVVEHRGAPHLVAAGVHLPWYQFYLLDVSAIILAITL 497
            |:.|:|:.|.:.:|||:..:|.|::|:.||:.|:|||||..|...|.|||::.|||...:|||.|
Mouse   436 YKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVL 500

  Fly   498 LPLLTLYAVSRNY---KSFRGIRAQKKEAKTE 526
            ..:..::.... |   |.|.|....||..|::
Mouse   501 TVVFIVFKCCA-YGCRKCFGGKGRVKKSHKSK 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B2	NP_001097859.4	egt	1..502	CDD:223071	153/523 (29%)
		UDPGT	31..497	CDD:278624	143/493 (29%)
Ugt1a2	NP_038729.1	UDPGT	28..524	CDD:278624	152/531 (29%)
		Glycosyltransferase_GTB_type	43..>175	CDD:299143	35/156 (22%)
		egt	<261..505	CDD:223071	89/245 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840799
Domainoid	1	1.000	259	1.000	Domainoid score	I1975
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2975
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm42461
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.790