Protein Alignment Ugt49B2 and ugt-54

DIOPT Version :10

• Sequence 1: NP_001097859.4
• Gene: Ugt49B2 / 42538
• FlyBaseID: FBgn0038886
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_501996.2
• Gene: ugt-54 / 188885
• WormBaseID: WBGene00012013
• Length: 527
• Species: Caenorhabditis elegans
• Alignment Length: 579
• Identity: 131/579 - (22%)
• Similarity: 245/579 - (42%)
• Gaps: 109/579 - (18%)

  Fly     5 MKLL--FVCLLGTGDGARILAPFFLPV--KSHFMMTDAIIRELVKRGHEVTFITPLSLAKEN--- 62
            ||.|  |:.|.|..:...||  |::.|  :||....:..|:.|:.|||.|..:    :|:.|
 Worm     1 MKTLLGFLILPGFANCLNIL--FYVSVIAQSHIPFHNTAIKVLLDRGHTVDLV----IAQLNEMV 59

  Fly    63 -------LGPNYREILLPKYDTWADISAMMKTKSALDMIDMSKLTHMRLAQHIGIKSTDFALAHP 120
                   :|.||         |:.........|:|..:.|:.....:.:|:.:......|.|...
 Worm    60 KLKFPNGVGKNY---------TFGYEDPNFYRKNAGHLSDIFVEKPIPMAEFLTFDDMTFNLCET 115

  Fly   121 EVQE---LIYAKDKKGKFDLLLVEQFH-------------NEGALMLGYIYE---------IPAI 160
            .|::   |.|.  |:|.:|:.|...:.             ::.:::...:::         .||.
 Worm   116 VVKDPNLLNYI--KQGNYDIGLSSDYDPCANILMHAGGVPSKASMVPTPLFQPQIVSAGLPSPAS 178

  Fly   161 TIATFAYA----NYFSQVFGFVNPLSYVPNVFLSCTDRMSLWERLENVVISTAEDVVREVSYYPQ 221
            ...|..|.    ::|:::|..:.   :..|::....   .|.|:..|:::.|
 Worm   179 VYGTVLYPKGDDSFFNRLFHLIR---HTYNIYFVAP---RLMEKYNNLLLET------------- 224

  Fly   222 QDAVIRKHFSSLLPRVPTVKQLEQNISVILLNSYMPLTSPRPMSQNMISVGGLHILPPKPLPEHI 286
                    |.   |..|:.:::|:|:.:||:||...:..|||:|..:..:||:.....:||.:..
 Worm   225 --------FG---PTFPSAEEIERNVDIILVNSNEIIEKPRPVSHKIKYIGGMGKKKAQPLNKEF 278

  Fly   287 KNYLDNAEHGAIYFSLGSQVRSADMPAEKLQIFLDVFASLKQ-RVLWKFEDDQLPNLPD------ 344
            .:.|..:..|.:.||.|:||.::.:|.|..:.|:..|..... ..|||::     ||.|
 Worm   279 NDILATSNKGVVLFSFGTQVATSKVPIEIRKNFVTAFKHFPDFSFLWKYD-----NLTDDAELFA 338

  Fly   345 ---NVKVEKWLPQADILAHPNVKVFIAHGGLFGMQEAVYHAVPVLGMPFYFDQDINIKAGQAAGY 406
               |:...:||||.|:|....||.||:|.||....|.....:|||.:|.:.||..|.....:...
 Worm   339 DSSNIHRVEWLPQTDLLGDNRVKAFISHMGLNSFLETSAAGIPVLAVPLFIDQQHNALNAVSRDI 403

  Fly   407 AIGLDYRTISKDQLKSALHALLKDPKYQANMMKASRIFRDRPLGAMDTAMYWINYVVEHRGAPHL 471
            .:.::...::.:.|.:||..||.:|||..|....|::..::|..:....:.|:.|..::.|...:
 Worm   404 GVIVERHQLTVENLVNALQKLLYNPKYGENAKMISKMMNEKPEQSERLFVDWVEYAAKNPGLHKI 468

  Fly   472 V-AAGVHLPWYQFYLLDVSAIILAITLLPLLTLYAVSRNYK---SFRGIRAQKKEAKTE 526
            : ..|..|..:.:|.:||..|::......|:.::......|   |.|.:|:.:.::|:|
 Worm   469 MNLPGAELTPFWYYSVDVILIVVLSLTSSLIIIWKTLSFIKCQISIRSVRSIEPKSKSE 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B2	NP_001097859.4	Glycosyltransferase_GTB-type	31..497	CDD:471961	114/515 (22%)
ugt-54	NP_501996.2	GT1_Gtf-like	17..443	CDD:340817	108/477 (23%)