Protein Alignment Ugt49B2 and ugt-61

DIOPT Version :9

• Sequence 1: NP_001097859.4
• Gene: Ugt49B2 / 42538
• FlyBaseID: FBgn0038886
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_504274.2
• Gene: ugt-61 / 185500
• WormBaseID: WBGene00018206
• Length: 530
• Species: Caenorhabditis elegans
• Alignment Length: 565
• Identity: 148/565 - (26%)
• Similarity: 247/565 - (43%)
• Gaps: 80/565 - (14%)

  Fly     5 MKLLFVCLLGTGDGARILAPFFLP--VKSHFMMTDAIIRELVKRGHEVTF--------------- 52
            |::|.|.|:..|..:......|:|  ..|.......:...|...||:||.
 Worm     1 MRVLSVFLVLVGVVSAYKFVLFVPNVANSQIQFNARVAEVLAIGGHDVTMLMVNHMAGFESNVKV 65

  Fly    53 ---------------ITPLSLAKENLGPNYREILLPKYDTWADISAMMKTKSALDMIDMSKLTHM 102
                           ||..|:.||.....|:.:.|      .|:..||...|.     |.||  :
 Worm    66 PKGVKTYQLDAAVEGITKQSIEKEQSAMLYKNMGL------KDMPQMMAMFSR-----MGKL--L 117

  Fly   103 RLAQHIGIKSTDFALAHPEVQELIYAKDKKGKFDLLLVEQFHNEGALMLGYIY--EIPA-ITIAT 164
            :....|.:::.:|         |.:.:|:  |||   |...|......||.|:  :||: :.:.:
 Worm   118 QDGCRIILRNKEF---------LKWLEDE--KFD---VAYTHIYSTCPLGLIHHAKIPSWVWLNS 168

  Fly   165 FAYANYFSQVFGFVNPLSYVPNVFLSCTDRMSLWERLENVVISTAEDVVREVSYYPQQDAVIRKH 229
            ....:|.||..|.....||||.|.::..|.|...:|.::.:......|:.......::.|:.||.
 Worm   169 GPLMDYVSQAVGVPILPSYVPPVLMASHDEMGFVQRTKSFIGHVLMSVMHRRISSDEETAIFRKE 233

  Fly   230 FSSLLPRVPTVKQLEQNISVILLNSYMPLTSPRPMSQNMISVGGLHI--LPPKPLPEHIKNYLDN 292
            .:.  |..|....:.....::::||......|||....:|::|||.:  ...|||....|. :..
 Worm   234 LND--PSFPHTMDIGAKCPLVIVNSNELYDLPRPTLAKVINIGGLGVGFDSAKPLTGEFKK-ISE 295

  Fly   293 AEHGAIYFSLGSQVRSADMPAEKLQIFLDVFASLKQ-RVLWKFEDDQLPN-LPDNVKVEKWLPQA 355
            ..:|.|.||.||...:.:||.......|:.||||.. :.:.::|.|.|.: ||:||.:.|||||.
 Worm   296 TGNGLIVFSFGSVAAAHEMPLAWKNSLLEAFASLPDYQFVMRYEGDDLKDRLPENVHLSKWLPQK 360

  Fly   356 DILAHPNVKVFIAHGGLFGMQEAVYHAVPVLGMPFYFDQDINIKAGQAAGYAIGLDYRTISKDQL 420
            |:|.|...|.||.|||...:|||:...||::.:....||..|.:..:..|:|:.::..||||:.:
 Worm   361 DLLLHEKTKAFITHGGYNSLQEAISAGVPLITIALMGDQPKNSQIAKKHGFAVNIEKGTISKETV 425

  Fly   421 KSALHALLKDPKYQANMMKASRIFRDRPLGAMDTAMYWINYVVEHRGAPHLVAAGVHLPWYQFYL 485
            ..||..:|::..|:..:.:.|.:.|.:|:...:..:.|..::.|.:...:||.||..|.:||::.
 Worm   426 VEALREILENDSYKQKVTRLSAMVRAQPMKPAERLLKWSEFLAEFKTLDNLVPAGQKLNFYQYHS 490

  Fly   486 LDVSA----IILAITLLPLLTLYAVSRNYKSFRGIRAQKKEAKTE 526
            |||..    ::|.:..:..|.|.||.|..       .:::|.||:
 Worm   491 LDVIGFLFLVVLVVFYIGFLILKAVFRKC-------CRRRETKTK 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B2	NP_001097859.4	egt	1..502	CDD:223071	140/539 (26%)
		UDPGT	31..497	CDD:278624	133/506 (26%)
ugt-61	NP_504274.2	UDPGT	37..519	CDD:278624	137/511 (27%)
		egt	<251..471	CDD:223071	70/220 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161529
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14157
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.740