Protein Alignment Ugt49B2 and ugt-42

DIOPT Version :10

• Sequence 1: NP_001097859.4
• Gene: Ugt49B2 / 42538
• FlyBaseID: FBgn0038886
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_503278.2
• Gene: ugt-42 / 185168
• WormBaseID: WBGene00017959
• Length: 527
• Species: Caenorhabditis elegans
• Alignment Length: 577
• Identity: 131/577 - (22%)
• Similarity: 226/577 - (39%)
• Gaps: 108/577 - (18%)

  Fly     1 MILFMKLLFVCLLG--TGDGARILAPFFLPVKSHFM--MTDAIIRELVKRGHEVTFITPLSLAK- 60
            |.|.:.|:||.|:.  :|....:::|.|....|.||  :.||    |.:.||.||.::.:..:|
 Worm     1 MNLLILLIFVFLISNISGFNYLVVSPAFGHSHSTFMGKLADA----LTEAGHNVTVLSIIVSSKF 61

  Fly    61 -------------------------ENLGPNYREILLPKYDTWADISAMMKT-KSALDMIDMSKL 99
                                     ||:..|.    ..:|  |.....:::| .|.|....||..
 Worm    62 RNISYTKLTKDIVVVETTNEQDQQAENMENND----FSRY--WTQEGTLLETIPSYLMFTKMSDH 120

  Fly   100 THMRLAQHIGIKSTDFALAHPEVQELIYAKDKKGKFDLLLVEQFHNEGALMLGYIYEIPAITIAT 164
            .:.....|          |.|:::   |.|..:.::|.:..|.:.:.|..:..|: |||.....|
 Worm   121 GYETFRNH----------ALPQME---YLKSHRPRYDAVFFESYLHTGKAIQEYL-EIPVFLPVT 171

  Fly   165 FAYANY-FSQVFGF-VNPLSYVPNVFLSCTDRMSLWERLENVVISTAEDVVREVSYY-------- 219
            ....:| .:::.|. |:| ||:...|.:..:.|:..||           |:..:|||
 Worm   172 SLTHDYRLAELIGEPVSP-SYLSGYFTNFGNIMNFQER-----------VINTLSYYLAQILISS 224

  Fly   220 --------PQQDAVIRKHFSSLLPRVPTVKQLEQNISVILLNSYMPLTSPRPMSQNMISVGGLHI 276
                    |.:|.::...:.    |.|          .:.:||...:..|||:....|.:||:.:
 Worm   225 PNWKTLQDPSKDLLVESEYY----RAP----------YVFINSNPYIDFPRPLLSKTIEIGGITV 275

  Fly   277 ----LPPKPLPEHIKNYLDNAEHGAIYFSLGSQVRSADMPAEKLQIFLDVFASLKQ-RVLWKFED 336
                |..:.:.|...|.|....|. :..|.|:..:|..||.......:.|..|.|. ..:||:|.
 Worm   276 DADALKSEKVDETWNNILKRRPHN-VLISFGTMFKSIHMPDSYKNNMVKVMKSFKNVTFIWKYES 339

  Fly   337 DQ--LPNLPDNVKVEKWLPQADILAHPNVKVFIAHGGLFGMQEAVYHAVPVLGMPFYFDQDINIK 399
            ::  ..|..:|:..:||.||..:||...:..|..||||..:.|..|...|.|..|.:.||..|.|
 Worm   340 EETSFANGAENIIFKKWTPQTALLADSRLSAFFTHGGLGSVNELSYLGKPALLCPLFADQVRNSK 404

  Fly   400 AGQAAGYAIGLD-YRTISKDQLKSALHALLKDPKYQANMMKASRIFRDRPLGAMDTAMYWINYVV 463
            .......:|.:. :...|.:.|:||||::|.|..|..|..|.::....:|....:..:....:..
 Worm   405 MLSRHNGSIEISKFNLESYNTLRSALHSILFDESYAENAEKLAKKLEFQPAKPKELFVRHAEFAA 469

  Fly   464 EHRGAPHLVAAGVHLPWYQFYLLDVSAIILAITLLPLLTLYAVSRNYKSFRGIRAQK 520
            .....|.|......:.:..::||||...:.:..:|.:|:|..:.|.......|:.::
 Worm   470 RFGEQPALDCNLRTMGFATYHLLDVVVCLTSFVVLVILSLVVIIRKIVQSLAIKMKR 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B2	NP_001097859.4	Glycosyltransferase_GTB-type	31..497	CDD:471961	117/520 (23%)
ugt-42	NP_503278.2	GT1_Gtf-like	20..464	CDD:340817	113/494 (23%)