DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt49B2 and ugt-7

DIOPT Version :9

Sequence 1:	NP_001097859.4	Gene:	Ugt49B2 / 42538	FlyBaseID:	FBgn0038886	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_504343.2	Gene:	ugt-7 / 182577	WormBaseID:	WBGene00015739	Length:	530	Species:	Caenorhabditis elegans

Alignment Length:	536	Identity:	143/536 - (26%)
Similarity:	230/536 - (42%)	Gaps:	87/536 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 ILAPFFLPVKSHFMMTDAIIRELVKRGHEVT-----FITPLSLAKENLGPNYREI---------- 70
            |::|.:  ..||......|...|...||||.     .:..|...|....|:.:.|
Worm    20 IISPIY--SYSHVKFMSNIADTLADHGHEVVVFQQQIVEALRDKKVIKNPDIKIINYEANTAGKE 82

  Fly    71 --------LLPKYDTWADISAMMKTKSALDMI--DMSK-LTHMRLAQHIGIKSTDFALAHPEVQE 124
                    .:.||  |....|  ...||.|..  .||| |.||.| |....||
Worm    83 FYRNRPKSSVTKY--WTTNQA--ANPSAADQFAEAMSKDLEHMCL-QVFEDKS------------ 130

  Fly   125 LIYAKDKKGKFDLLLVEQFHNEGALMLGYIYEIPAITIATFAYANY--FSQVFGFVNPLSYVPNV 187
             ::...|...||:||.|.|...| |.||...:||: ||...|.:..  .....|..:.|:::|..
Worm   131 -LHTMLKSEHFDVLLAEPFDPCG-LYLGDYLKIPS-TIVAMASSRIDPVQWALGQPSGLNFIPGP 192

  Fly   188 FLSCTDRMSLWERLENVVISTAEDVVREVSYYPQQDAVIRKHFSSLLPRVPTVKQLE-QNISVIL 251
            .....:...:|:|:.||.:            :..:..:.|..:.:||.::.....|| :||..|:
Worm   193 DSKYGEESGVWDRINNVWM------------FFMRTRMFRAVYWNLLDKLRFKTGLEIRNIDEIV 245

  Fly   252 -------LNSYMPLTSPRPMSQNMISVGGLHI----LPPKPLPEHIKNYLDNAEHGAIYFSLGSQ 305
                   .||...|..|.|.....:.:||..:    ...:.|||::||.|....: .::.|.||.
Worm   246 AESAYLFYNSNPYLDFPFPSLTKCVPIGGFSMNTTNWKSENLPENLKNILQKRPN-TVFISFGSV 309

  Fly   306 VRSADMPAEKLQIFLDVFASLKQ-RVLWKFEDDQ----LPNLPDNVKVEKWLPQADILAHPNVKV 365
            :||||||.|.....::|...:.. ..:||:||::    ..|:|:||.:.|||||..:||...|.:
Worm   310 IRSADMPQEYKNAIIEVTKLMSDVTFIWKYEDEKDEEMRGNIPENVHLMKWLPQPALLADSRVSL 374

  Fly   366 FIAHGGLFGMQEAVYHAVPVLGMPFYFDQDIN----IKAGQAAGYAIGLDYRTISKDQLKSALHA 426
            ||.||||..:.|..|...|.:.:|.:|||.:|    .:.|.|..|:   .:...:..:||..:..
Worm   375 FITHGGLGSIMEVAYSGKPAIVIPLFFDQPMNGEMLRRHGGAEVYS---KFELSNAKKLKKVIQN 436

  Fly   427 LLKDPKYQANMMKASRIFRDRPLGAMDTAMYWINYVVEHRGAPHLVAAGVHLPWYQFYLLDVSAI 491
            ::::|||.||..|.|.:.:.:|:..::..:....:..|.:..|.|.....||.::||:.||:.|.
Worm   437 MIQNPKYLANAKKLSNLLQKQPINPIERLVKHAEFAAEFKKLPELDPYSRHLNFFQFFFLDIVAT 501

  Fly   492 ILAITLLPLLTLYAVS 507
            :|.:.:|..|.:|.::
Worm   502 LLILFMLSALFVYWIT 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B2	NP_001097859.4	egt	1..502	CDD:223071	141/529 (27%)
Ugt49B2	NP_001097859.4	UDPGT	31..497	CDD:278624	138/514 (27%)
ugt-7	NP_504343.2	egt	1..477	CDD:223071	130/494 (26%)
ugt-7	NP_504343.2	UDPGT	27..521	CDD:278624	141/527 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161535
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.740