DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt49B2 and ugt-9

DIOPT Version :9

Sequence 1:	NP_001097859.4	Gene:	Ugt49B2 / 42538	FlyBaseID:	FBgn0038886	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_504312.1	Gene:	ugt-9 / 178883	WormBaseID:	WBGene00020587	Length:	533	Species:	Caenorhabditis elegans

Alignment Length:	560	Identity:	126/560 - (22%)
Similarity:	212/560 - (37%)	Gaps:	75/560 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 MKLLFVCLLGTGDGARILAPFFLPVKSHFMMTDAIIRELVKRGHEVTFITPLSLAKENLG----- 64
            :.:|.|..|.:.....:..|.|  ..||......:...:...||.||...|..:|.:|..
Worm     7 LSILLVISLVSCKNILVYNPIF--GYSHAKFVSQLANIIADHGHNVTVFQPFHIALKNTDGLIKN 69

  Fly    65 ----------PNYREILLPKYDTWADI-SAMMKTKSALDMIDMSKLTHMRLAQHIGIKSTDFALA 118
                      .:|.|:|..|..|:.|. .:.:.....|....|.|.......|    .:|.....
Worm    70 KNIEIINYYPDHYAELLKKKTPTFPDFWDSHLMNNPVLSSFLMPKALGGEFEQ----TTTQLFQD 130

  Fly   119 HPEVQELIYAKDKKGKFDLLLVEQFHNEGALMLGYIYEIPAITIATFAYANYFSQVFGFVNPLSY 183
            ...:.:|     |...||:||.|.|...| ..:..:.|||:|.:.:..........||..:.|.|
Worm   131 QKILNDL-----KNRNFDVLLAETFEIAG-FYIADLLEIPSIPLMSAVRLPIIDSAFGQPSILGY 189

  Fly   184 VPNVF------------LSCTDRMSLWERLENVVISTAEDVVREVSYYPQQDAVIRKHFSSLLPR 236
            .|..:            |:...|:..|......:.....|.:::...:|
Worm   190 FPQQYSKVAPEAGFLDRLNDLYRIFFWNLTTQRLCQFQNDFIQKAIGHP---------------- 238

  Fly   237 VPTVKQLEQNISVILLNSYMPLTSPRPMSQNMISVGGLHILPPK-----PLPEHIKNYLDNAEHG 296
            ||..:.|.:...:.:.||...|....|.:..::.|||:.|...|     .|.|..:|.|...| .
Worm   239 VPHWRDLVKESPIYITNSNSYLDFAVPTTATIVHVGGITIDLEKMRHVAALTEEYENILAERE-S 302

  Fly   297 AIYFSLGSQVRSADMPAEKLQIFLDVFASLKQ-RVLWKFEDDQLP---NLPDNVKVEKWLPQADI 357
            .::.|.||.:||.:||.......:.:|.||.. ..:||:|.|.:.   .||.||.::||:||..:
Worm   303 TVFISFGSVIRSYEMPDNFKAGIIKMFKSLPDVTFIWKYEKDDVKFQNRLPKNVHLKKWVPQPSL 367

  Fly   358 LAHPNVKVFIAHGGLFGMQEAVYHAVPVLGMPFYFDQDINIKAGQAAGYAIGLD-YRTISKDQLK 421
            ||...||:|:.||||....|..|...|.|.:|.:.||..|.......|.|:..| :.....::|.
Worm   368 LADKRVKLFVTHGGLGSTMEVAYTGKPALMVPIFGDQPNNADMLARHGGAVAYDKFDLADGEKLT 432

  Fly   422 SALHALLKDPKYQANMMKASRIFRDRPLGAMDTAMYWINYVVE---HRG-APHLVAAGVHLPWYQ 482
            ..:..::.:.||:.|..:..::...:|:......|..:.:.:|   ||. .|.:...|:    ..
Worm   433 KTVRDMVTNSKYEVNAQELLKVLSKQPIDPKLNLMKHLEFAMEFPKHRSQVPAINRTGL----IA 493

  Fly   483 FYLLDVSAIILAITLLPLLTLYAVSRNYKSFRGIRAQKKE 522
            .|.|||..::...::..|..::.:....:....:|..|:|
Worm   494 HYYLDVIGVLTLASIFGLFVIFKILNILRKMISLRKVKRE 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B2	NP_001097859.4	egt	1..502	CDD:223071	123/538 (23%)
Ugt49B2	NP_001097859.4	UDPGT	31..497	CDD:278624	117/507 (23%)
ugt-9	NP_504312.1	egt	20..462	CDD:223071	109/470 (23%)
ugt-9	NP_504312.1	UDPGT	30..532	CDD:278624	119/532 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161643
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.740