Protein Alignment Ugt49B2 and ugt-22

DIOPT Version :10

• Sequence 1: NP_001097859.4
• Gene: Ugt49B2 / 42538
• FlyBaseID: FBgn0038886
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_502633.1
• Gene: ugt-22 / 178330
• WormBaseID: WBGene00007455
• Length: 534
• Species: Caenorhabditis elegans
• Alignment Length: 537
• Identity: 134/537 - (24%)
• Similarity: 233/537 - (43%)
• Gaps: 60/537 - (11%)

  Fly     2 ILFMKLLFVCLLGTGDGARILAPFFLPVKSHFMMTDAIIRELVKRGHEVTFITP-LSLAKENLGP 65
            :|.:.||....:|..:..:||....|...||..|..|:...|...||::|.:.| :...:||.
 Worm     7 LLPLLLLLGSFVGLTEPYKILMYTNLFGHSHIKMLGAVSDTLTDAGHDLTVLMPVIDFKQENK-- 69

  Fly    66 NYREILLPKYDTWADISAMMKTKSALDM---IDMSKLTHMRLAQHIGIKSTD-----FALAHPEV 122
                            :||..||:.:.:   .|:||...........:.:||     |.:.|...
 Worm    70 ----------------TAMKSTKNIIKIQPGQDISKTIETMEKFMTQLWTTDNSNPLFMVFHAPA 118

  Fly   123 QELIYA-------KDKK-------GKFDLLLVEQFHNEGALMLGYIYEIPAITIATFAYANYFSQ 173
            ...|:|       :||:       ..|||.:.|.|......:...|.....:.:.:.:..::.|:
 Worm   119 MSAIFASQCRKVLEDKELIERLRAENFDLAITEPFDTCAYALFEAIKIRAHVAVLSCSRLDHVSK 183

  Fly   174 VFGFVNPLSYVPNVFLSCTDRMSLWERLENVVISTAEDVVREVSYYPQQDAVIRKHFSSLLPRVP 238
            ..|.....||||....:..:||::|:|..|::.....|.:  .||...:|..:.|   .::|.|.
 Worm   184 AIGQPIAPSYVPGTQSTHGERMTIWQRFMNILHFLMGDFL--FSYIGDEDFKVAK---EIIPGVR 243

  Fly   239 TVKQLEQNISVILLNSYMPLTS-PRPMSQNMISVGGLHILPPK---PLPEHIKNYLDNAEHGAIY 299
            :.:::....|.|..| ::||.. |.|....:|.:||:.:...|   .|||.....|...:.. |.
 Worm   244 SWREVLPEASFIFTN-HIPLMDFPAPTFDKIIPIGGISVKTQKKSLELPEKWNKILGLRKKN-IL 306

  Fly   300 FSLGSQVRSADMPAEKLQIFLDVFASLKQ-RVLWKFED--DQLPNLPDNVKVEKWLPQADILAHP 361
            .|.||..||||||....|..|.|..|:.. ..:||:|:  |.|.:..|||.:..||||.::|..|
 Worm   307 VSFGSNARSADMPEHFKQNVLKVAESMPDVTFIWKYENEKDTLADHLDNVYLGDWLPQNELLGDP 371

  Fly   362 NVKVFIAHGGLFGMQEAVYHAVPVLGMPFYFDQDINIKAGQAAGYAIGLDYRTI-SKDQLKSALH 425
            .:.:|:.||||..:.|......|.:.:|.:.||..|....:..|.|..|....: :.:.:::.:.
 Worm   372 RLSLFVTHGGLASVTELALMGKPAVMVPLFADQARNANMLKRHGGAAVLHKTDLGNAETIRNTIK 436

  Fly   426 ALLKDPKYQANMMKASRIFRDRPLGAMDTAMYWINYVVEHRGAPHLVAAGVHLPWYQFYLLDVSA 490
            .:|::.||:.|..:.:.:..::|....||.:..:.:..:....|.:...|.|..:.::||||
 Worm   437 KVLENEKYRVNAERLAEMLNNQPTNPKDTLIKHVEFAAKFGQLPSMDPYGRHQSYIEYYLLD--- 498

  Fly   491 IILAITLLPLLTLYAVS 507
             |::|.|:.:||...:|
 Worm   499 -IISIALVLILTTSFIS 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B2	NP_001097859.4	Glycosyltransferase_GTB-type	31..497	CDD:471961	123/496 (25%)
ugt-22	NP_502633.1	GT1_Gtf-like	24..469	CDD:340817	117/469 (25%)