DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt49B2 and ugt-58

DIOPT Version :9

Sequence 1:	NP_001097859.4	Gene:	Ugt49B2 / 42538	FlyBaseID:	FBgn0038886	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_496059.2	Gene:	ugt-58 / 174507	WormBaseID:	WBGene00009450	Length:	533	Species:	Caenorhabditis elegans

Alignment Length:	555	Identity:	144/555 - (25%)
Similarity:	242/555 - (43%)	Gaps:	89/555 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 FVCLLGT------GDGARILAPFFLPVKSHFMMTDAIIRELVKRGHEVTFITPLSLAKENLGPNY 67
            ::.||||      ||...|.:..: ||  |......:.|||.:|||:||::        .:||..
Worm     4 WLLLLGTIGWVTAGDVLFIPSTLY-PV--HAQTMSVLARELAERGHKVTWL--------EIGPER 57

  Fly    68 REILLPKY---DTWADISAMMKTKSALDMIDMSKLT-HMRL---------AQHIG----IKSTDF 115
            .:|:|.:.   :.|   .|....::..::......| |..|         .|..|    |:..|.
Worm    58 SDIVLHQQVSREFW---PAQFGDRTLQEIYQFKNHTSHSELWNPQYTNENEQTTGWLASIRLCDS 119

  Fly   116 ALAHPEVQELIYAKDKKGKFDLLLVEQF--------HNE-GALMLG-----YIYEIPAITIATFA 166
            .|:.           .|.|||.::.:||        :|. |.||.|     |||..........|
Worm   120 VLSR-----------SKSKFDKMVEKQFSTVIVDDLYNSCGVLMAGLKKSVYIYWSMTGLRTESA 173

  Fly   167 YANYFSQVFGFVNPLSYVPNVFLSCTDRMSLWERLENVVISTAEDVVREVSYYPQQDAVIRKHFS 231
            :||...      :|.||:|......||.::..:||.||.....:..:.:....|:.|||.:|::
Worm   174 WANQSP------SPPSYLPVAGTGLTDDLTFSQRLYNVASYFKQLYIHQHIVQPRIDAVFQKYY- 231

  Fly   232 SLLPRVPTVKQLEQNISVILLNSYMPLTSPRPMSQNMISVGGLHILPPKPLPEHIKNYLDNAEHG 296
               |.|.:..::|:|.|:..:|:.......||....:..:|.:....||.||:...:::.....|
Worm   232 ---PGVESTFEIERNASINFVNTPPIFDFSRPYMPRVNFIGAIQCRKPKELPKEFTSWISAYPDG 293

  Fly   297 AIYFSLGSQVRSADMPAEKLQIFLDVFASLKQRV-LWKFEDDQLPNLPDNVKVEKWLPQADILAH 360
            .:..|.|..|:....|....|.:||.|..|...: :|:.......|||.|:.|:.|||..|:|.|
Worm   294 FVVLSTGFTVQWNKSPEHIRQAYLDTFKYLPNLLFIWQTGLPNSSNLPSNLLVKPWLPLQDLLGH 358

  Fly   361 PNVKVFIAHGGLFGMQEAVYHAVPVLGMPFY---FDQDINIKAGQAAGYAIGLDYRTISKDQLKS 422
            ...:..::||||..:.|:|||.|||:|:|..   :|..:.|.|..:   .:.::....|.:.|.:
Worm   359 QKCRCHVSHGGLNSVIESVYHGVPVVGVPLTSRGYDNLLRITARDS---GVMVEKSEFSGEILTA 420

  Fly   423 ALHALLKDPKYQANMMKASRIFRDRPLGAMDTAMY----WINYVVEHRGAPHLVAAGVHLPWYQF 483
            |::.::::.||:..|:    ||:|..:....|.:|    |:.::..|:..||..:...||.:.|:
Worm   421 AINEVIENEKYKKEML----IFQDMVIDVPYTELYHAAFWVEFIERHQEVPHARSGADHLNFLQY 481

  Fly   484 YLLDVSAIILAITLLPLLTLYAVSRNYKSFRGIRA 518
            :|:||.|....:....|..:|...|..  ||.||:
Worm   482 FLVDVIAFFFFVIFCTLSIIYYTIRTV--FRTIRS 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B2	NP_001097859.4	egt	1..502	CDD:223071	138/537 (26%)
Ugt49B2	NP_001097859.4	UDPGT	31..497	CDD:278624	128/504 (25%)
ugt-58	NP_496059.2	UDPGT	17..485	CDD:278624	130/509 (26%)
ugt-58	NP_496059.2	Glycosyltransferase_GTB_type	<200..462	CDD:299143	72/272 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14290
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810