Protein Alignment Ugt49B2 and Ugt3a2

DIOPT Version :10

• Sequence 1: NP_001097859.4
• Gene: Ugt49B2 / 42538
• FlyBaseID: FBgn0038886
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_997099.2
• Gene: Ugt3a2 / 105887
• MGIID: 2146055
• Length: 523
• Species: Mus musculus
• Alignment Length: 561
• Identity: 147/561 - (26%)
• Similarity: 256/561 - (45%)
• Gaps: 95/561 - (16%)

  Fly     7 LLFVCLLGTGDGARILAPFFLPVKSHFMMTDAIIRELVKRGHEVTFITPLSLAKENLGPNYREIL 71
            ||.|.||   :.|:||....|.. ||:::.:.:.:.|...||:|     :.|..|.
Mouse    14 LLEVLLL---EAAKILTISTLSA-SHYILMNRVSQILQGGGHDV-----IKLLYEG--------- 60

  Fly    72 LPKYDTWADISAMMKTKSALDMID------------------MSKLTHMRLAQHIGIKSTDF--- 115
                   .||....|..|:..:|:                  :.:..:.|...|..:|...:
Mouse    61 -------GDIPDFRKENSSYQVINWRLPEDQQKTFENRWHRLIDEYAYGRSKYHTLLKIHQYFAD 118

  Fly   116 ----ALAHPEVQELIYAKDKKGKFDLLLVEQFHNEGALM---LG--YIYEIPAITIATFAYANYF 171
                .|:..::.||:    :|..|||:|::.......|:   ||  ::..:|    ..|:|.:
Mouse   119 LCSHLLSRKDIMELL----QKENFDLVLLDSMDLCSFLIVEKLGKRFVSFLP----FQFSYMD-- 173

  Fly   172 SQVFGFVN-PLSYVPNVFLSCTDRMSLWERLENVVI-----STAEDVVREVSYYPQQDAVIRKHF 230
               ||..| ||||.|......||:|..|.|::|:::     ....|:      :.|....:::||
Mouse   174 ---FGLPNAPLSYAPVYGSGLTDQMDFWGRVKNILMFFHFTKKRRDI------FSQYGNTVQEHF 229

  Fly   231 SSLLPRVPTVKQLEQNISVILLNSYMPLTSPRPMSQNMISVGGLHILPPKPLPEHIKNYLDN-AE 294
            :.  ...|.:..|.....:..:||...|...||:..|.:.||||...|.:|:|:.:::::.. .:
Mouse   230 AE--GSQPVLSDLLLKAELWFVNSDFALDFARPLFPNTVYVGGLLDKPVQPIPQDLEDFISQFGD 292

  Fly   295 HGAIYFSLGSQVRSADMPAEKLQIFLDVFASLKQRVLWKFEDDQLP---NLPDNVKVEKWLPQAD 356
            .|.:..:|||.| |.....|.::.....||.|.|.|||..:....|   :|..|||:..||||.|
Mouse   293 SGFVLVALGSVV-SMIQSKEIIKEMNSAFAHLPQGVLWTCKSSHWPKDVSLAPNVKIMDWLPQID 356

  Fly   357 ILAHPNVKVFIAHGGLFGMQEAVYHAVPVLGMPFYFDQDINIKAGQAAGYAIGLDYRTISKDQLK 421
            :||||::::|:.|||:..:.|||:|.||::|:||:.||..|:...:|....:.:..:|:..:...
Mouse   357 LLAHPSIRLFVTHGGMNSVMEAVHHGVPMVGIPFFGDQPENMVRVEAKNLGVSIQLQTLKAESFL 421

  Fly   422 SALHALLKDPKYQANMMKASRIFRDRPLGAMDTAMYWINYVVEHRGAPHLVAAGVHLPWYQFYLL 486
            ..:..:::|.:|:...|.:..|.:..||......:.||:::::..||.||.......||::.|:|
Mouse   422 LTMKEVIEDQRYKTAAMASKVIRQSHPLTPAQRLVGWIDHILQTGGAAHLKPYAFQQPWHEQYML 486

  Fly   487 DVSAIILAITL----LPLLTLYAVSRNYKSFRGIRAQKKEA 523
            ||...:|.:||    |.:..|.||:|    :..|..:.|:|
Mouse   487 DVFLFLLGLTLGTLWLSVKVLVAVTR----YLSISRKVKQA 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B2	NP_001097859.4	Glycosyltransferase_GTB-type	31..497	CDD:471961	128/505 (25%)
Ugt3a2	NP_997099.2	Glycosyltransferase_GTB-type	24..488	CDD:471961	128/507 (25%)