Protein Alignment Ugt49B2 and Ugt2b34

DIOPT Version :9

• Sequence 1: NP_001097859.4
• Gene: Ugt49B2 / 42538
• FlyBaseID: FBgn0038886
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_705826.1
• Gene: Ugt2b34 / 100727
• MGIID: 2140962
• Length: 532
• Species: Mus musculus
• Alignment Length: 538
• Identity: 167/538 - (31%)
• Similarity: 262/538 - (48%)
• Gaps: 71/538 - (13%)

  Fly     2 ILFMKLLFVCLLGTGDGARILAPFFLPVK-SHFMMTDAIIRELVKRGHEVTFITP---LSLAKEN 62
            :|.:.|......|:|.|.::|.   .|:: ||::....|:.||:|:||||..:.|   ||...:|
Mouse     9 LLLLLLQLSGFFGSGTGGKVLV---WPMEFSHWLNLKTILDELLKKGHEVMVLRPSASLSYEVDN 70

  Fly    63 LG-------------PNYREIL----------LPKYDTWADISAMMKTKSALDMIDMSKLTHMRL 104
            ..             ....||.          |||...|.                    ..:.|
Mouse    71 TSAIEFETYPTSYSLSELEEIFWESLKKYIYELPKQSFWG--------------------YFLML 115

  Fly   105 AQHIGIKSTDFALAHPEV---QELIYAKDKKGKFDLLLVEQFHNEGALMLGYIYEIPAI-TIATF 165
            .:.:.:.|..|.....:|   :||: .|.:|.:||::|.:.|...|.| |..:.:||.: ::..|
Mouse   116 QEMVWVDSKYFESLCKDVVFNKELM-TKLQKSRFDVILADPFIPCGDL-LAEVLKIPLVYSLRFF 178

  Fly   166 AYANYFSQVFGFVNPLSYVPNVFLSCTDRMSLWERLENVVISTAED----VVREVSYYPQQDAVI 226
            ..:.|.....|...|.||||.|....:|||:..||:.||:.....|    ...|.::
Mouse   179 PGSTYEKYSGGLPLPPSYVPVVMSELSDRMTFMERVRNVIYMLCFDFWFQTFNEKNW-------- 235

  Fly   227 RKHFSSLLPRVPTVKQLEQNISVILLNSYMPLTSPRPMSQNMISVGGLHILPPKPLPEHIKNYLD 291
            .:.::.:|.|..|:.:......:.|:.:|..|..|.|:..|...:||||..|.||||:.|::::.
Mouse   236 NQLYTEVLGRPTTLSETMAKADIWLIRTYWDLEFPHPVLPNFDFIGGLHCRPAKPLPKEIEDFVQ 300

  Fly   292 NA-EHGAIYFSLGSQVRSADMPAEKLQIFLDVFASLKQRVLWKFEDDQLPNLPDNVKVEKWLPQA 355
            :: |||.:.|||||.|.|  :..|:..:.....|.:.|:|||:||..:...|..|.::.||:||.
Mouse   301 SSGEHGVVVFSLGSMVGS--ITEERANVIAAGLAQIPQKVLWRFEGKKPETLGSNTRLYKWIPQN 363

  Fly   356 DILAHPNVKVFIAHGGLFGMQEAVYHAVPVLGMPFYFDQDINIKAGQAAGYAIGLDYRTISKDQL 420
            |:|.|...:.||.|||..|:.||:||.:||:|:|.:.||..||...:|.|.|:.||:.|:|...|
Mouse   364 DLLGHSKTRAFITHGGTNGIYEAIYHGIPVVGIPLFGDQYDNIVHLKAKGAAVRLDFLTMSSTDL 428

  Fly   421 KSALHALLKDPKYQANMMKASRIFRDRPLGAMDTAMYWINYVVEHRGAPHLVAAGVHLPWYQFYL 485
            .:||..:..||.|:.|.|:.|||..|:|:..:|.|::||.:|:.|:||.||..|...|.|.|::.
Mouse   429 HTALKTVTNDPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWVQYHS 493

  Fly   486 LDVSAIILAITLLPLLTL 503
            |||...:||..|..:..|
Mouse   494 LDVLGFLLACVLTVMFIL 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B2	NP_001097859.4	egt	1..502	CDD:223071	166/535 (31%)
		UDPGT	31..497	CDD:278624	158/500 (32%)
Ugt2b34	NP_705826.1	UDPGT	27..529	CDD:278624	162/520 (31%)
		egt	<272..510	CDD:223071	97/239 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840772
Domainoid	1	1.000	259	1.000	Domainoid score	I1975
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2975
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm42461
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.790