Protein Alignment Ugt49B2 and ugt2b5

DIOPT Version :10

• Sequence 1: NP_001097859.4
• Gene: Ugt49B2 / 42538
• FlyBaseID: FBgn0038886
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001170816.3
• Gene: ugt2b5 / 100384902
• ZFINID: ZDB-GENE-100402-3
• Length: 527
• Species: Danio rerio
• Alignment Length: 561
• Identity: 158/561 - (28%)
• Similarity: 271/561 - (48%)
• Gaps: 76/561 - (13%)

  Fly     1 MILFMKLLFVCLLGTGDGARILAPFFLPVKSHFMMTDAIIRELVKRGHEVTFITP----LSLAKE 61
            ::.|:.||.|  ...|....||.  :....||::....::..|:.|||.||.:.|    ...|||
Zfish     4 VVCFLSLLTV--FSAGQCGNILV--WYTEGSHWINLKIVLDTLLDRGHNVTVLVPDGALFMKAKE 64

  Fly    62 NLGPNYREILLPKYDTWADISAMMKTKSALDM--------------IDMSKLTHMRL------AQ 106
            :...:|:...:              :|||.||              :|.|....:::      :|
Zfish    65 SDRFSYQHFSV--------------SKSAQDMQDFFDELMRFSVFEMDNSSFLEIQMKFFNLGSQ 115

  Fly   107 H--IGIKSTDFALAHPEVQELIYAKDKKGKFDLLLVEQFHNEGALMLGYIYEIPAITIATFAYAN 169
            |  :.:...|..|..||:.:    |.||||||::|.:..:....:|...: .:|.:....|:.|:
Zfish   116 HQDMSLSYCDGILKSPELMD----KLKKGKFDVVLSDPMYPCSDIMAEEL-NVPLVYTFRFSVAH 175

  Fly   170 YFSQVFGFV-NPLSYVPNVFLSCTDRMSLWERLENVVISTAEDVVREVSYYPQQDAVIR------ 227
            ...::.|.: .|.||||......|||||..||:.|::            :|..||.:.|
Zfish   176 AAERMCGQIPAPPSYVPGAMSKLTDRMSFTERIFNML------------FYLSQDTLSRLIWRRF 228

  Fly   228 -KHFSSLLPRVPTVKQLEQNISVILLNSYMPLTSPRPMSQNMISVGGLHILPPKPLPEHIKNYLD 291
             .:::....|..:..::.....:.|:.:|.....|||...|...:||||..|.||||:.::.::.
Zfish   229 DNYYTEYFGRSTSYCEMMGRADIWLIRTYWDFEFPRPFVPNFKYIGGLHCTPAKPLPKDMEEFVQ 293

  Fly   292 NA-EHGAIYFSLGSQVRSADMPAEKLQIFLDVFASLKQRVLWKFEDDQLPNLPDNVKVEKWLPQA 355
            :: :.|.:.|:|||.:..  :|.|.........|.:.|:|||::..::...|.:|.::.||:||.
Zfish   294 SSGDDGIVVFTLGSMIDK--VPKEMSNRIASALAQIPQKVLWRYGGEKPDTLGENTRIYKWMPQN 356

  Fly   356 DILAHPNVKVFIAHGGLFGMQEAVYHAVPVLGMPFYFDQDINIKAGQAAGYAIGLD-YRTISKDQ 419
            |:|.||..:.||.|||..|:.||:||.||::|:|.:.||..|:......|.|:.:| .:::...:
Zfish   357 DLLGHPKTRAFITHGGTNGVYEAIYHGVPMVGIPLFGDQPDNMVHMTTRGAAVVVDSIKSMQPQE 421

  Fly   420 LKSALHALLKDPKYQANMMKASRIFRDRPLGAMDTAMYWINYVVEHRGAPHLVAAGVHLPWYQFY 484
            |...|:.::.||.|:.|.|:.|||..|||:..:|.:::||.:|:.::||.||.....:|.|||::
Zfish   422 LVDKLNTVINDPSYKENAMRLSRIHHDRPMKPLDESVFWIEFVMRNKGAKHLRVEAHNLTWYQYH 486

  Fly   485 LLDVSAIILAITLLPLLTLYAVSRNY---KSFRGIRAQKKE 522
            .|||.|.:..:..|.|...:.:::.:   ..||..|..|||
Zfish   487 CLDVFAFLTTVLTLVLYICFKMAKFFIMRCCFRSKRKSKKE 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt49B2	NP_001097859.4	Glycosyltransferase_GTB-type	31..497	CDD:471961	143/501 (29%)
ugt2b5	NP_001170816.3	None