Sequence 1: | NP_732637.1 | Gene: | bap / 42537 | FlyBaseID: | FBgn0004862 | Length: | 382 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_079141.2 | Gene: | NANOG / 79923 | HGNCID: | 20857 | Length: | 305 | Species: | Homo sapiens |
Alignment Length: | 244 | Identity: | 62/244 - (25%) |
---|---|---|---|
Similarity: | 94/244 - (38%) | Gaps: | 67/244 - (27%) |
- Green bases have known domain annotations that are detailed below.
Fly 67 PLCCRDLGLYKLTQPKEIQPS---ARQPSNY--LQYYAAAMDNNNHHHQATGTSNSSAADYMQRK 126
Fly 127 LAYFGSTLAAPLDMRRCTSNDSDCDSPPPLSSSPSESPLSHDGSGLS-------RKKRSRAAFSH 184
Fly 185 AQVFELERRFAQQRYLSGPERSEMAKSLRLTETQVKIWFQNRRYKTKRKQIQQHEAALLGASKRV 249
Fly 250 PVQVLVREDGSTTYAHMAAPGAGHGLDPALINIYRHQ--LQLAYGGLPL 296 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
bap | NP_732637.1 | Homeobox | 178..231 | CDD:278475 | 23/52 (44%) |
NANOG | NP_079141.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..96 | 23/120 (19%) | |
COG5576 | 74..191 | CDD:227863 | 39/139 (28%) | ||
HOX | 95..151 | CDD:197696 | 24/55 (44%) | ||
Required for DNA-binding. /evidence=ECO:0000269|PubMed:25825768 | 122..151 | 12/28 (43%) | |||
8 X repeats starting with a Trp in each unit | 196..240 | 62/244 (25%) | |||
Sufficient for transactivation activity. /evidence=ECO:0000250 | 196..240 | 62/244 (25%) | |||
Sufficient for strong transactivation activity. /evidence=ECO:0000250 | 241..305 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.910 |