Protein Alignment bap and NKX2-1

DIOPT Version :9

• Sequence 1: NP_732637.1
• Gene: bap / 42537
• FlyBaseID: FBgn0004862
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_001073136.1
• Gene: NKX2-1 / 7080
• HGNCID: 11825
• Length: 401
• Species: Homo sapiens
• Alignment Length: 434
• Identity: 113/434 - (26%)
• Similarity: 151/434 - (34%)
• Gaps: 161/434 - (37%)

  Fly     5 ESAGVSAAMAG--------------LSKSLTTPFSINDILTRSNPETRRMSSVDSEPEPEKLKPS 55
            ::.|..||..|              :|...|||||::|||:                      |.
Human     8 KARGWEAAAGGRSSPGRLSRRRIMSMSPKHTTPFSVSDILS----------------------PL 50

  Fly    56 SDRERSISKSPPLCCRDLGLYKLTQPKEIQPSARQPSNYLQYYAAAMDNNNHHHQATGTSNSSAA 120
            .:..:.:..........|..|:       |..|..|:..:|.:|.     .||...|...:.:||
Human    51 EESYKKVGMEGGGLGAPLAAYR-------QGQAAPPTAAMQQHAV-----GHHGAVTAAYHMTAA 103

  Fly   121 DYMQRKLAYFGSTLAAPLDMRRCTSNDSDCDSPPPLSSS-------------------PSESPLS 166
            ...|...:..|.         .|..|..:....||...:                   |:.|...
Human   104 GVPQLSHSAVGG---------YCNGNLGNMSELPPYQDTMRNSASGPGWYGANPDPRFPAISRFM 159

  Fly   167 HDGSGLS------------------------RKKRSRAAFSHAQVFELERRFAQQRYLSGPERSE 207
            ...||::                        |:|| |..||.|||:||||||.||:|||.|||..
Human   160 GPASGMNMSGMGGLGSLGDVSKNMAPLPSAPRRKR-RVLFSQAQVYELERRFKQQKYLSAPEREH 223

  Fly   208 MAKSLRLTETQVKIWFQNRRYKTKR--------KQIQ---------------QHEAALLGASKRV 249
            :|..:.||.|||||||||.|||.||        :|:|               |.:.|...:.:||
Human   224 LASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQQLQQDSGGGGGGGGTGCPQQQQAQQQSPRRV 288

  Fly   250 PVQVLVREDGSTTYAHMAAPGA----GHGLDPALINIYRHQLQLAY----------GGLPLPQMQ 300
            .|.|||: ||....|...||||    ||....|     :||.|.|.          ||..|..
Human   289 AVPVLVK-DGKPCQAGAPAPGAASLQGHAQQQA-----QHQAQAAQAAAAAISVGSGGAGLGA-- 345

  Fly   301 MPFPYFYPQHKVPQPIPPPTQSSSFVTASSASSSPVPIPIPGAV 344
                  :|.|:      |.:...|...|..|:|   |..:.|.|
Human   346 ------HPGHQ------PGSAGQSPDLAHHAAS---PAALQGQV 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bap	NP_732637.1	Homeobox	178..231	CDD:278475	35/52 (67%)
NKX2-1	NP_001073136.1	Homeobox	194..247	CDD:278475	36/53 (68%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0842
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810