DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bap and Vax2

DIOPT Version :9

Sequence 1:	NP_732637.1	Gene:	bap / 42537	FlyBaseID:	FBgn0004862	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_072159.1	Gene:	Vax2 / 64572	RGDID:	621133	Length:	292	Species:	Rattus norvegicus

Alignment Length:	249	Identity:	68/249 - (27%)
Similarity:	107/249 - (42%)	Gaps:	46/249 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 HQATGTSNSSAADYMQRKLAYFGSTLAAPLDMRRCTSNDSDCDSPPPLSSSP-SESPLSHDGSG- 171
            |:......:.......|::|  |::.::|...|   .:..|.|....|..:. ....|..|..|
  Rat    28 HRGAEDLRADTGSTSPREIA--GTSASSPAGSR---ESGGDSDGQQALGETDHCRRILVRDAKGT 87

  Fly   172 -----------LSRKKRSRAAFSHAQVFELERRFAQQRYLSGPERSEMAKSLRLTETQVKIWFQN 225
                       |.|.||:|.:|:..|::.||..|.:.:|:.|.||:|:|:.|.|:|||||:||||
  Rat    88 IREIVLPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQN 152

  Fly   226 RRYKTKRKQIQQHEAALLGASKRVPVQVLVREDGSTTYAHMAAPGAGHGLDPA-LINIYRHQLQL 289
            ||.|.|:.|.:..|       ||.         .|:.:...|.......|:.. |:::.|....|
  Rat   153 RRTKQKKDQSRDLE-------KRA---------SSSAFEAFATSNVLRLLEQGRLLSVPRAPSLL 201

  Fly   290 AYG-GLP-LPQMQMPFPYFYPQHKVPQPIPPPTQSSSFVTASSASSSPVPIPIP 341
            |.. ||| |...........|::...:..|.|         |:::|||:|.|:|
  Rat   202 ALSPGLPGLTAGHRGTSLGDPRNSSQRLNPMP---------SASASSPLPPPLP 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bap	NP_732637.1	Homeobox	178..231	CDD:278475	26/52 (50%)
Vax2	NP_072159.1	vax upstream domain	74..101		4/26 (15%)
		homeobox	102..161		29/58 (50%)
		Homeobox	105..158	CDD:278475	26/52 (50%)
		vax downstream domain	182..193		2/10 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	212..241		6/37 (16%)
		vax terminal domain	266..274
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910