Protein Alignment bap and NKX2-4

DIOPT Version :9

• Sequence 1: NP_732637.1
• Gene: bap / 42537
• FlyBaseID: FBgn0004862
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_149416.1
• Gene: NKX2-4 / 644524
• HGNCID: 7837
• Length: 354
• Species: Homo sapiens
• Alignment Length: 417
• Identity: 109/417 - (26%)
• Similarity: 150/417 - (35%)
• Gaps: 150/417 - (35%)

  Fly    16 LSKSLTTPFSINDILTRSNPETRRMSSVDSEPEPEKLKPSSDRERSISKSPPLCCRDLG---LYK 77
            ||...|||||::|||:               |..|..|..|.   ::..:||.....||   .|:
Human     3 LSPKHTTPFSVSDILS---------------PIEETYKKFSG---AMDGAPPGLGAPLGAAAAYR 49

  Fly    78 LTQPKEIQPSAR-------QPSNYLQYY---------AAAMDNNNHHHQATGTS---NSSAADYM 123
            ...|   .||::       |||:.:..:         |||......:|...|.|   :.:...|.
Human    50 APPP---GPSSQAATVAGMQPSHAMAGHNAAAAAAAAAAAAAAAATYHMPPGVSQFPHGAMGSYC 111

  Fly   124 QRKLAYFGSTLAAPLDMRRCTSNDSDCDSPPPLSSSPSE-------------------------- 162
            ...|...|...|....||...:......:|.|..||.|.
Human   112 NGGLGNMGELPAYTDGMRGGAATGWYGANPDPRYSSISRFMGPSAGVNVAGMGSLTGIADAAKSL 176

  Fly   163 SPLSHDGSGLSRKKRSRAAFSHAQVFELERRFAQQRYLSGPERSEMAKSLRLTETQVKIWFQNRR 227
            .||....:..:.:::.|..||.|||:||||||.||:|||.|||..:|..:.||.|||||||||.|
Human   177 GPLHAAAAAAAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHR 241

  Fly   228 YKTKR-------KQIQQHEAALLG-------ASKRVPVQVLVR-----EDGSTTYAHMAAPGAGH 273
            ||.||       :|:||...  ||       :.:||.|.|||:     ::|::|
Human   242 YKMKRQAKDKAAQQLQQEGG--LGPPPPPPPSPRRVAVPVLVKDGKPCQNGAST----------- 293

  Fly   274 GLDPALINIYRHQLQLAYGGLPLPQMQMPFPYFYPQHKVPQPIPPPTQSSSFVTASSASSSPVPI 338
                                 |.|....|.|        |.|.|.|         .....||.|.
Human   294 ---------------------PTPGQAGPQP--------PAPTPAP---------ELEELSPSPP 320

  Fly   339 PIPGAVRPQRTPCPSPNGQMMSVESGA 365
            .:.|           |.|.:.::::.|
Human   321 ALHG-----------PGGGLAALDAAA 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bap	NP_732637.1	Homeobox	178..231	CDD:278475	35/52 (67%)
NKX2-4	NP_149416.1	Homeobox	192..245	CDD:278475	35/52 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	246..329		28/144 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0842
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810