DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bap and hmx3a

DIOPT Version :9

Sequence 1:	NP_732637.1	Gene:	bap / 42537	FlyBaseID:	FBgn0004862	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_571709.2	Gene:	hmx3a / 60310	ZFINID:	ZDB-GENE-001020-1	Length:	297	Species:	Danio rerio

Alignment Length:	337	Identity:	92/337 - (27%)
Similarity:	133/337 - (39%)	Gaps:	100/337 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 PETRRMSSVDSEPEPEKLKPSSDRERSISKSPPLCCRDL----GLYKLTQPKEIQ-PSARQPSNY 94
            |||.:.:...::..|..:|...:.:...||..|:.....    |.:.|:|..||. |....|
Zfish     2 PETTQDTCASAKDSPFFIKNLLNSDSKPSKPKPILAPTKAGLDGSFSLSQVGEINFPRFELP--- 63

  Fly    95 LQYYAAAMDNNNHHHQATGTSNSSAADYMQRKLA-YFGSTLAAPLDMRRC----TSNDS------ 148
                               |...:...|::|..| ::..||:|...:.|.    .:.||
Zfish    64 -------------------TQRFALPAYLERASAWWYPYTLSASAHLHRTEAAQKARDSSPTTGT 109

  Fly   149 DCDSPP-PLSSSPS----------------ESPLSHDG---SGLS--------------RKKRSR 179
            |.|||. .|.|.|.                |...:.||   .|:.              |||::|
Zfish   110 DRDSPELVLKSDPDAKDDEDDNKSGDEIVLEESDTEDGKKEGGIDDWKKSDDGADKKPCRKKKTR 174

  Fly   180 AAFSHAQVFELERRFAQQRYLSGPERSEMAKSLRLTETQVKIWFQNRRYKTKRKQIQQHEAALL- 243
            ..||.:|||:||..|..:||||..||:.:|.||.||||||||||||||.|.||:...:.|||.|
Zfish   175 TVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAAELEAANLS 239

  Fly   244 --GASKRVPVQVLVREDGSTTYAHMAAPGAGHGLDPALINIYRHQLQLAYGGLPLPQMQMPFPY- 305
              .|.:.|.|.:|..|:.::...:.|                        |.:|:.|..:.||:
Zfish   240 HAAAQRIVRVPILYHENSASESTNTA------------------------GNVPVSQPLLTFPHP 280

  Fly   306 FYPQHKVPQPIP 317
            .|..|.:...:|
Zfish   281 VYYSHPIVTSVP 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bap	NP_732637.1	Homeobox	178..231	CDD:278475	33/52 (63%)
hmx3a	NP_571709.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	24..43		3/18 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	96..172		15/75 (20%)
		Homeobox	173..226	CDD:278475	33/52 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910