DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bap and pitx2

DIOPT Version :9

Sequence 1:	NP_732637.1	Gene:	bap / 42537	FlyBaseID:	FBgn0004862	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_001017227.1	Gene:	pitx2 / 549981	XenbaseID:	XB-GENE-482492	Length:	345	Species:	Xenopus tropicalis

Alignment Length:	283	Identity:	70/283 - (24%)
Similarity:	109/283 - (38%)	Gaps:	42/283 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 LGLYKLTQPKEIQPSARQPSNYLQYYAAAMDNNNHHHQATGTSNSSAADYMQRKLAYFGSTLAAP 137
            |.|..|...|....|:....::.|:......:..||||........|...:         ::|:.
Frog     8 LHLDHLVGSKLATASSHHQHHHQQHQQHQHHHQQHHHQQHQQPQPQAVTLV---------SMASS 63

  Fly   138 LDMR--RCTS-----NDSDCDSPPPLS-----SSPSESPLSHDGSGLSRKKRSRAAFSHAQVFEL 190
            |..|  .|.:     ..||..||....     .|.:|...:.|.|...|::|.|..|:..|:.||
Frog    64 LGQRSGECKARLEVHTISDTSSPEAADKDKSHQSKNEDSSTDDPSKKKRQRRQRTHFTSQQLQEL 128

  Fly   191 ERRFAQQRYLSGPERSEMAKSLRLTETQVKIWFQNRRYK-TKRKQIQQHEAALLGASKRVPVQVL 254
            |..|.:.||.....|.|:|....|||.:|::||:|||.| .||::.||.|....|...:....:.
Frog   129 EATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQ 193

  Fly   255 VREDGSTTYAHMAAPGAGHGLDPALINIYRHQLQLAYGGLPLPQMQMPFPYFYPQHKVPQPIPPP 319
            ..:|...:|::  ...|..||..|.::                  ...||:|...:..|......
Frog   194 PYDDMYPSYSY--NNWAAKGLTSASLS------------------TKSFPFFNSMNVNPLSSQSM 238

  Fly   320 TQSSSFVTASSASSSPVPIPIPG 342
            ..|.:.:::.|.||..||..:.|
Frog   239 FSSPNSISSMSMSSGMVPSAVTG 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bap	NP_732637.1	Homeobox	178..231	CDD:278475	22/53 (42%)
pitx2	NP_001017227.1	XRCC4	<84..144	CDD:284132	17/59 (29%)
		Homeobox	117..169	CDD:278475	22/51 (43%)
		OAR	303..320	CDD:281777
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910