Protein Alignment bap and NKX1-1

DIOPT Version :9

• Sequence 1: NP_732637.1
• Gene: bap / 42537
• FlyBaseID: FBgn0004862
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_001277008.1
• Gene: NKX1-1 / 54729
• HGNCID: 24975
• Length: 448
• Species: Homo sapiens
• Alignment Length: 413
• Identity: 105/413 - (25%)
• Similarity: 144/413 - (34%)
• Gaps: 119/413 - (28%)

  Fly     5 ESAGVSAAMAGLSKSLTTPFSINDILTRSNPETRRMSSVDSEP-EPEKLKPSSDR----ERSISK 64
            |.||.:...|.|.   .|.||:.|||..:...:||...|...| .|....|.:..    ..:.|.
Human    66 EGAGAARPAAPLR---PTSFSVLDILDPNKFNSRRRRCVLLGPVAPAACAPCASAPCAPAPAASG 127

  Fly    65 SPPLCCRDLGLYKLTQPKEIQPSARQPSNYLQYYAA--AMDNNNHHHQATGTSNSSAADYMQR-- 125
            .||. ..:|....|.....:..:..:|.|....:.|  |..|:.:.:.:.|..:|.:||....
Human   128 RPPR-AEELERRALAGAGGVGAAGAEPPNAGDPFKAGEAETNDTNGYSSGGGGHSPSADSGDEVP 191

  Fly   126 ---------------------------KLAYFGS-------TLAAP---LDMRRC---TSNDSDC 150
                                       .|...||       |.|:|   :|....   ..|....
Human   192 DDEDDDEDEAPETEAARGAEEARGGGGGLGARGSGCQGAAETDASPGATVDEAAAPGPRENSPVA 256

  Fly   151 DSPPPLSSSPSESPLSHDGSGLSRK---------------KRSRAAFSHAQVFELERRFAQQRYL 200
            ..||..:::|..:..:..|:..:.|               :|:|.||::.|:..||.:|...|||
Human   257 QGPPGGAAAPGGAGTTPQGTATAAKPKRKRTGSDSKSGKPRRARTAFTYEQLVALENKFKATRYL 321

  Fly   201 SGPERSEMAKSLRLTETQVKIWFQNRRYKTKRKQIQQHEAALLGASKRVPVQVLVREDGSTTYAH 265
            |..||..:|.||.||||||||||||||.|.|::.        .||....|          |....
Human   322 SVCERLNLALSLSLTETQVKIWFQNRRTKWKKQN--------PGADTSAP----------TGGGG 368

  Fly   266 MAAPGAGHGLD-PALINIYRHQLQLAYGGL----PLPQMQMPF----PYFYPQH---------KV 312
            ...||||.|.. |              |||    |.|.|..|.    |..||.|         ::
Human   369 GPGPGAGPGTGLP--------------GGLSPLSPSPPMGAPLGMHGPAGYPAHGPGGLVCAAQL 419

  Fly   313 PQPIPPPTQSSSFVTASSASSSP 335
            |. :..|...|.||..|....:|
Human   420 PF-LSSPAVLSPFVLGSQTYGAP 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bap	NP_732637.1	Homeobox	178..231	CDD:278475	31/52 (60%)
NKX1-1	NP_001277008.1	Homeobox	300..352	CDD:278475	31/51 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910