Protein Alignment bap and PAX6

DIOPT Version :9

• Sequence 1: NP_732637.1
• Gene: bap / 42537
• FlyBaseID: FBgn0004862
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_001355839.1
• Gene: PAX6 / 5080
• HGNCID: 8620
• Length: 503
• Species: Homo sapiens
• Alignment Length: 469
• Identity: 99/469 - (21%)
• Similarity: 161/469 - (34%)
• Gaps: 151/469 - (32%)

  Fly     6 SAGVSAAMAGLSK----SLT-----------TPFSINDILTRSNPETRRMSS--VDSEPEPE--- 50
            :|.:..|:||.::    |||           :|.|.:.:.|..:....::..  |:..|.|:
Human    43 AAEIKRAVAGANRLPALSLTCGGRTCLWLKPSPGSDSHVCTGGHSGVNQLGGVFVNGRPLPDSTR 107

  Fly    51 ----KLKPSSDRERSISK----SPPLCCRDLGLYKLT---QPKEI---QPSARQP---SNYLQYY 98
                :|..|..|...||:    |.....:.||.|..|   :|:.|   :|....|   |...||.
Human   108 QKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYK 172

  Fly    99 -------------------AAAMDN-------NNHHHQATGTSNSSAADYMQRKLA--------- 128
                               ....||       |..............||.|..||.
Human   173 RECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSW 237

  Fly   129 ------YFGSTLAAPLDMRRCTSNDSDCDSPPPLSSSPSESPLSHDGSGLSRK-KRSRAAFSHAQ 186
                  |.|:::........|...:...::...:||:..:|..:.....|.|| :|:|.:|:..|
Human   238 GTRPGWYPGTSVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQ 302

  Fly   187 VFELERRFAQQRYLSGPERSEMAKSLRLTETQVKIWFQNRRYKTKRKQ---IQQHEAALLGASKR 248
            :..||:.|.:..|.....|..:|..:.|.|.::::||.|||.|.:|::   .|:.:|:      .
Human   303 IEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQAS------N 361

  Fly   249 VPVQVLVREDGSTT-YAHMAAP---------GAGHG-LDPALINIYRHQLQLAYGGLPLPQMQMP 302
            .|..:.:....||: |..:..|         |:..| .|.||.|        .|..||      |
Human   362 TPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTN--------TYSALP------P 412

  Fly   303 FPYFYPQHKVPQPIPPPTQSSSFV-----------------------------------TASSAS 332
            .|.|...:.:|...|.|:|:||:.                                   |.|:..
Human   413 MPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGL 477

  Fly   333 SSP---VPIPIPGA 343
            .||   ||:.:||:
Human   478 ISPGVSVPVQVPGS 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bap	NP_732637.1	Homeobox	178..231	CDD:278475	17/52 (33%)
PAX6	NP_001355839.1	PAX	85..209	CDD:128645	23/123 (19%)
		Homeobox	295..348	CDD:395001	17/52 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910