DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bap and pax3

DIOPT Version :9

Sequence 1:	NP_732637.1	Gene:	bap / 42537	FlyBaseID:	FBgn0004862	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	XP_012825755.1	Gene:	pax3 / 448464	XenbaseID:	XB-GENE-482740	Length:	486	Species:	Xenopus tropicalis

Alignment Length:	196	Identity:	59/196 - (30%)
Similarity:	89/196 - (45%)	Gaps:	47/196 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   148 SDCDSPPPLSSSPSESPLSHDGSGLSRKKRSRAAFSHAQVFELERRFAQQRYLSGPERSEMAKSL 212
            ||.||.|.|       ||..      :::|||..|:..|:.||||.|.:..|.....|.|:|:..
Frog   207 SDIDSEPDL-------PLKR------KQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRA 258

  Fly   213 RLTETQVKIWFQNRRYKTKRKQIQQHEAALLGASKRVPVQVLVREDGSTTYAHMAAPGAGHGLDP 277
            :|||.:|::||.|||.:. |||        .||::.:....|:             |||   ..|
Frog   259 KLTEARVQVWFSNRRARW-RKQ--------AGANQLMAFNHLI-------------PGA---FPP 298

  Fly   278 ALI-NIYRHQL-QLAYGGLPLPQMQMPFPYFYPQHKV--PQPIPPPTQSSSFVTASSASSSPVPI 338
            |.: .:..:|| :.:|....:||....     |.:.|  |||:||.:...|.:.::..|||...:
Frog   299 AAMPALPTYQLSETSYQPTSIPQAVSD-----PSNTVHRPQPLPPSSVHQSSLPSNPESSSAYCL 358

  Fly   339 P 339
            |
Frog   359 P 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bap	NP_732637.1	Homeobox	178..231	CDD:278475	22/52 (42%)
pax3	XP_012825755.1	PAX	35..162	CDD:238076
		Homeobox	224..278	CDD:365835	22/54 (41%)
		Pax7	349..393	CDD:372070	4/11 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910