DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bap and UNCX

DIOPT Version :9

Sequence 1:	NP_732637.1	Gene:	bap / 42537	FlyBaseID:	FBgn0004862	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_001073930.1	Gene:	UNCX / 340260	HGNCID:	33194	Length:	531	Species:	Homo sapiens

Alignment Length:	335	Identity:	80/335 - (23%)
Similarity:	119/335 - (35%)	Gaps:	103/335 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 HHH--QATGTSNSSAADYMQRKLA---YFGSTLAA--------PLDMRRC-TSNDSD----CDSP 153
            |||  :..|....|||.......:   ..|.:.||        ||....| ...|..    .||.
Human    30 HHHVYELAGHQLQSAAAAASVPFSIDGLLGGSCAAAASVVNPTPLLPAACGVGGDGQPFKLSDSG 94

  Fly   154 PPLSSSPSESPLSHDGSGLSRKKRSRAAFSHAQVFELERRFAQQRYLSGPERSEMAKSLRLTETQ 218
            .|...||.           .:::|:|..|:..|:.|||:.|.:..|.....|..:|..|.|.|::
Human    95 DPDKESPG-----------CKRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESR 148

  Fly   219 VKIWFQNRRYKTKRK---------------------------QIQQHEAALLGASKRVPVQVLVR 256
            |::||||||.|.::|                           :|.:.|...:...||...:.|::
Human   149 VQVWFQNRRAKWRKKENTKKGPGRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRKHEKKLLK 213

  Fly   257 EDGSTTYAHMAAPGAGHGLDPALINIYRHQLQLAYGGLPLPQMQMPFPYFYPQHKVPQPIPPPTQ 321
            ..|    .|:.:||   ||  :|.:..........|||      .|.|        |:|.||..:
Human   214 SQG----RHLHSPG---GL--SLHSAPSSDSDSGGGGL------SPEP--------PEPPPPAAK 255

  Fly   322 SSSFVTASSASSSPVP---IPIPGAVRP-----QRT-----PCP-----------SPNGQMMSVE 362
            ......:.:|.::|.|   .|.||...|     ||:     |.|           .|...:.:||
Human   256 GPGAHASGAAGTAPAPPGEPPAPGTCDPAFYPSQRSGAGPQPRPGRPADKDAASCGPGAAVAAVE 320

  Fly   363 SGAESVHSAA 372
            .||..:..|:
Human   321 RGAAGLPKAS 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bap	NP_732637.1	Homeobox	178..231	CDD:278475	21/52 (40%)
UNCX	NP_001073930.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	87..107		5/30 (17%)
		Homeobox	108..161	CDD:306543	21/52 (40%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	161..312		33/173 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	324..344		1/7 (14%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	401..531
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910